Neoplastic Skin Diseases Flashcards
What are the four classifications of skin tumours?
Epithelial
Spindle cell
Round cell
Melanocytic
Why may a papilloma regress?
May regress spontaneously due to cytotoxic immune response
What are the characteristics of tumours of the hair follicles?
Most often solitary, benign, slow growing masses in older animals
List four types of sebaceous gland masses
Sebaceous hyperplasia
Sebaceous adenoma
Sebaceous adenocarcinoma
Sebaceous cysts
What paraneoplastic change may an anal sac apocrine gland tumour cause?
Paraneoplastic hypercalcaemia
Which species are fibromas mostly seen in?
Cats
List the causes of fibrosarcomas in young and old cats?
Young cat - feline sarcoma virus/feline leukaemia virus (multicentric)
Old cat - injection sites (solitary)
What is the most common equine skin tumour and what is it caused by?
Sarcoid - bovine papilloma virus
What are the histopathological features of sarcoids?
Hyperplastic epidermis - whorls and bundles of collagen/fibroblasts
What is the most common dog skin tumour and what age of dogs are they seen in?
Histiocytoma - young dogs (2-4 years)
What do histiocytomas look like?
Strawberry buttons - solitary, raised, benign
What are the histopathological features of a histiocytoma?
Sheet macrophage-like cells, dendritic Langerhans cells, highly mitotic and lymphoid infiltrate at the base.
In which horses and what is the age of horses that equine melanomas are most commonly seen?
Grey horses > 6 years