Neoplastic Diseases: Malignant Flashcards

1
Q

Cancerous growths originate from

A

Various types of tissue

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2
Q

If a cancerous growth is epithelial in origin than it is classified a

A

Carcinoma

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3
Q

What is the most common cancerous growth that arises from epithelial tissue

A

Adenocarcinoma

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4
Q

Cancerous growths that originate from connective tissue are classified as

A

Sarcomas

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5
Q

Primary malignancy is

A

Area (organ) of origin

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6
Q

Secondary malignancy is

A

AKA metastatic
Extension of CA to other areas
Has various routes of spread

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7
Q

What are the various routes of spread that metastatic disease uses

A

Blood
Lymphatics
Direct invasion

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8
Q

Proven causes of malignant neoplasms are from

A

Exposure to carcinogens

Radiation

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9
Q

What are the high risk factors for malignant neoplasms

A

Viruses
Familial tendencies
Environment
Hormones

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10
Q

What sonographic signs would create the suspicion of a malignant mass

A
Hypoechoic halo 
Hypoechoic solid liver mass
Multiple liver masses 
High velocity signals; being able to pick up an arterial waveform instead of venous 
Hypervascular lesions 
Lymphadenopathy
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11
Q

What are the primary malignant neoplasms of the liver

A

Hepatocellular carninoma (HCC,hepatoma)
Hemangiosarcoma (angiosarcoma)
Epithelial hemangioendothelioma
Hepatoblastoma

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12
Q

What is the most common primary malignancy of the liver

A

HCC

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13
Q

Who is more at risk of developing HCC

A

Males in their 6th decade of life

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14
Q

What the 3 forms of HCC

A

Focal solitary
Focal multiple
Diffuse infiltration

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15
Q

What are the risk factors of HCC

A
Alcoholic cirrhosis 
Hep B 
Hep C
Toxic metabolites 
Metabolic disorders
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16
Q

What are the symptoms of HCC

A

RUQ pain
Weight loss
Abdominal swelling (ascites)
Hepatomegaly

17
Q

What is the sonographic appearance of HCC

A

Variable; often Hypoechoic with anarchic halo
High velocity signals on doppler
Uncommon to have calcifications
Portal and hepatic venous invasion

18
Q

What lab values are elevated with HCC

A

ALP
AST
ALT

19
Q

What lab value in increased in cases of HCC

A

AFP

20
Q

What is the prognosis of HCC

A

5 year survival rate about 1%

21
Q

Hemangiosarcoma is

A

Extremely rare and aggressive, occurs most often in 60-80 yrs olds