Neoplastic Diseases: Benign Flashcards
Neoplasms
Tumor/ lesion ~abnormal tissue growth ~diffuse or focal ~benign or malignant ~distinct mass or ill-defined
Abnormal tissue growth is due to
Cells proliferating at a faster rate
Malignant neoplasms can be
Primary or metastatic
Primary malignancies
Mass that originates from a organ
Metastatic malignancies
Mass that originates from a organ and spreads to a different organ
Benign neoplasms
~typically asymptomatic ~have no altered lab tests ~well defined and encapsulated ~slow growing, does not metastasize ~hypovascular or avascular
Benign neoplasms of the liver
Hemangioma
Focal nodular hyperplasia
Adenomas
Lipoma
Hemangioma is a tumor of
blood vessels
The most common benign tumor of the liver
Hemangioma
Hemangioma are
~Women>Men (5:1)
~Asymptomatic
Hemangioma may increase in size during
Pregnancy or with the use of estrogen therapy(HRT’s)
What is the sonographic appearance of a hemangioma
Small (typically <3cm) Well defined Homogenous Hyperechoic Can include a heterogenous central component or hypoechoic central area
When using Doppler on a hemangioma, will it register the slow flow?
No, because the flow is so slow that the Doppler cannot go low enough to register it which is why flow in a hemangioma is not typically detected with ultrasound
What does a hemangioma require
6-month follow up to detect any change
Echogencity is always relative to
Whether the organ is health or not
FNH
Focal nodular hyperplasia
What is focal nodular hyperplasia
Hyperplasia lesion containing normal liver tissue
FNH is >in women than men probably because it is
Influenced by hormones
Is FNH asymptomatic or symptomatic
Asymptomatic
What is the sonographic appearance of FNH
Subtle- “stealth lesion”
<8cm
Central area w/ decreased echogenicity (central scar)
Doppler flow centrally
Because FNH is a stealth “leasion” what do you look for
Contour abnormalities
Displaced vessels
What is the appearance of FNH on a sulpher colloid scan
Hot or warm
Are adenomas more or less common than FNH
Less
Adenomas are linked to
Oral contraceptives
Type 1 GSD
Von Gierke’s disease
Adenomas can cause
Hemorrhage or infarct; with extreme amount of pain
Adenomas are
Usually asymptomatic
What is the sonographic appearance of an adenoma
Non-specific; usually hyperechoic but can be variable
Measures 8-15cm
Solid, solitary and well encapsulated
Doppler shows central area of colour
What is the appearance of an adenoma on a Sulphur colloid scan
Cold
Lipomas in the liver are
Very rare
Usually asymptomatic
What is the sonographic appearance of a liver lipoma
Hyperechoic, very similar appearance to a hemangioma
What are the different ways to test for benign neoplasms of the liver
Contrast enhanced CT or MRI Red blood scintigraphy Sulphur Colloid scan Micro bubble enhanced sonography Biopsy
A Sulphur Colloid Scan is a
Nuclear medicine test
What is the treatment for a liver hemangioma
Repeat US in 3-6months to check for changes
What is the treatment for FNH
Conservative, depending on size
What is the treatment for a liver adenoma
Surgery is recommended due to risk of rupture
What is the treatment for an liver lipoma
Conservative
Are benign neoplasms of the spleen rare
Yes
What is another name for hemangioma
Cavernous hemangioma
Cavernous hemangioma are
Congenital
Most common benign neoplasm of the spleen ‘
Asymptomatic
Are cavernous hemangioma on US a conclusive finding
No, due to its variable appearance
What is the sonographic appearance of a cavernous hemangioma
Variable
Hyperechoic to complex with cystic degeneration
Hamartoma are
Rare
Arise from lymphoid tissue
What is the sonographic appearance of a hamartoma
Homogeneous
Solid
Echogenic
Not encapsulated
Lymphangioma are
Rare
Arise from a lymphatic malformation
What is the sonographic appearance of a lymphangioma
Variable