Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

EOR OB/GYN > Neoplasms - Ovarian CA and vulvar/vaginal CA > Flashcards

Neoplasms - Ovarian CA and vulvar/vaginal CA Flashcards

1
Q

what cancer has the highest mortality of all gynecological cancers

A

ovarian CA - presents at late stage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

RF ovarian CA

A

family history of ovarian cancer, BRCA1 or BRCA2, age greater than 50 years, infertility, early menarche, late menopause, or nulliparity

endometriosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

sx ovarian CA

A

early - asx
later - abdominal bloating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

PE ovarian CA

A

ascites
noticeable abdominal distention
palpable pelvic mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

types of ovarian CA

A

epithelial
germ cell
stromal cel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

MC form of ovarian CA and what are it’s associations

A

epithelial

associated with women over the age of 50 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

germ cell ovarian CA associations

A

far less common and is associated with women between the ages of 15 and 19 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

stromal cell ovarian CA and its associations

A

seen in women of any age group

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

dx ovarian CA

A

pelvic ultrasound and is confirmed with a biopsy

labs –> elevated CA-125

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

tx ovarian CA

A

surgical excision of the tumor, a hysterectomy, a bilateral salpingo-oophorectomy with selective lymphadenectomy, and postoperative chemotherapy for those with advanced-stage cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

is there screening for ovarian CA

A

no

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What tumor markers would you expect to be elevated in a patient with cervical cancer?

A

Beta-hCG, squamous cell carcinoma, and serum sialyl-Tn (STN)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

second most common gynecologic malignancy

A

ovarian CA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

US features for ovarian CA

A

solid component within the mass, increased Doppler flow to the solid component, and irregular septations within the mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What finding on thoracentesis of a patient with a pleural effusion suggests a diagnosis of epithelial ovarian cancer?

A

Malignant müllerian cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what CA125 level is considered elevated

A

> 35 U/mL is considered elevated

17
Q

fourth most common gynecologic malignancy

A

vulvar CA

18
Q

MC type of vulvar CA

A

squamous cell carcinoma

19
Q

average age of onset vulvar CA

A

68

20
Q

RF vulvar CA

A

human papillomavirus, prior vulvar or cervical intraepithelial neoplasia, prior history of cervical cancer, cigarette smoking, and immunodeficiency syndromes
lichen sclerosis

21
Q

MC sx vulvar CA

A

vulvar lesion

22
Q

squamous cell carcinoma lesions in vulvar CA

A

firm; white, red, or skin-colored; nodules, papules, or plaques; and have varying degrees of erosion or ulceration

23
Q

evaluation of vulvar CA

A

assessing for risk factors, characterizing the lesion on exam, performing a colposcopy to detect subclinical lesions, and performing a biopsy

24
Q

types of vulvar CA

A

squamous cell carcinoma (most common), melanoma, basal cell carcinoma, Bartholin cyst adenocarcinoma, and extramammary Paget disease of the vulva

25
Q

Paget disease of the vulva

A

a rare adenocarcinoma affecting the apocrine or eccrine glands

26
Q

sx of Paget disease of the vulva

A

pruritus, soreness, irritation, and burning. If the area can be visualized, patients may report redness or thickened skin. In some cases, they may report bleeding, although patients are often unable to accurately locate the course of the bleed (wether vulvar, vaginal, or urinary)

27
Q

PE Paget disease of vulva

A

vulvar or perineal erythema and scale (typically well demarcated). It can present as a macule, patch, plaque, or ulceration. It is often tender or pruritic and may be friable

vulvar lesion with an eczematoid appearance

28
Q

dx Paget disease of vulva

A

colposcopic biopsy of the vulva

Under colposcopy, acetowhite changes after the application of acetic acid may indicate the presence of dysplasia and assist in performing the most accurate vulvar biopsy

29
Q

tx Paget disease of the vulva

A

wide local excision. Margins of 2–3 cm are recommended to reduce the risk of recurrence

30
Q

once Paget disease of the vulva is identified, a complete workup to rule out other malignancies is recommended. what malignancies should be ruled out

A

endometrial, endocervical, vaginal, bladder, breast, and rectal cancers

31
Q

Paget disease of the vulva is also known as

A

extramammary Paget disease

32
Q

MC sx of Paget dz of the vulva

A

vulvar pruritus

33
Q

melanoma vulvar CA presents as

A

black nodules with irregular borders that evolve rapidly

34
Q

tx vulvar CA

A

surgical excision with or without radiation and chemotherapy

35
Q
A

EOR OB/GYN (18 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions