L&D Complications pt 2 Flashcards
Preterm labor
a common complication of pregnancy and is defined as delivery of a child between 20 and 37 weeks of gestation
RF preterm labor
prior cervical procedures
age < 17
age > 35
low socioeconomic status
poor access to care
interpersonal violence
poor nutrition
T2DM
asthma
HTN
kidney issues
thyroid issues
non physiologic anemia
MDD
vaginal/cervical infections
illicit drugs
smoking
multiple gestation etc
nhibition of acute preterm labor is often accomplished with
tocolytics such as indomethacin, nifedipine, or terbutaline. Magnesium sulfate can also be given, as well as corticosteroids for surfactant formation and antibiotics for group B Streptococcus infection
Tocolytics and delaying labor
Tocolytics are unlikely to delay labor for more than 48 hours once spontaneous induction of labor has begun
dx preterm labor
diagnosed based on the presence of regular and painful uterine contractions that are approximately 5 minutes apart for an hour and accompanied by cervical change (dilation or effacement) prior to 37 weeks of gestational age
specific measurements of cervical change that meet the criteria for preterm labor
at least one of the following: cervical dilation ≥ 3 cm, cervical length < 20 mm on transvaginal ultrasound, or cervical length between 20 and 30 mm with a positive fetal fibronectin
women w atypical sx of preterm labor, including pelvic pressure, cramping, or vaginal discharge, should be evaluated with what
fetal fibronectin test
why is fetal fibronectin test helpful when it is negative
this test is helpful when it is negative, as a negative test is associated with a 93–97% probability the patient will not deliver within 7–14 days
ppl w a negative test (less than 50 ng/mL) can typically be discharged home. Before being discharged home, the patient should be under observation for a period of 6–12 hours
management for preterm labor at ≥ 34 weeks gestation
women should be monitored for 4–6 hours to assess for progressive cervical dilation or effacement.
Women who progress should be admitted for delivery, and women without progression can be discharged if fetal well-being has been assured and there are no signs of obstetric complications, such as placental abruption, prelabor rupture of membranes, or intra-amniotic infection.
Women who are at ≥ 34 weeks gestation should not be given antenatal corticosteroids or tocolytic (anticontraction) agents.
management for preterm labor < 34 weeks
Women who are < 34 weeks of gestation presenting with preterm labor should be treated with tocolytic therapy for 48 hours, antibiotics for group B streptococcal prophylaxis, and antenatal corticosteroids for 48 hours
what are women given for neuroprotection (against cerebral palsy) if they present preterm labor between 24-32 weeks
magnesium sulfate
the tocolytic agent typically used for women with preterm labor who are between 24 and 32 weeks gestational age
indomethacin
the tocolytic agent typically used for women with preterm labor who are between 32 and 34 weeks gestational age
nifedipine
when are antenatal steroids recommended for preterm labor
between 22 weeks and 33 6/7 weeks gestational age
antenatal corticosteroids
betamethasone
dexamethasone
Why should indomethacin not be used for more than 48 hours in women who are in preterm labor?
Use for more than 48 hours can cause premature closure of the ductus arteriosus
is the fetal fibronectin test recommended in asx women
the fetal fibronectin test is not recommended in asymptomatic women since it has low sensitivity
what can be used to prevent preterm birth in women with shortened cervix
Progesterone and the cervical cerclage procedure