Neoplasms from first aid Flashcards
What neoplasm is associated with acanthosis nigricans?
visceral malignancies, esp. stomach
What cancer is associated with actinic keratosis?
squamous cell carcinoma
What canceris associated with cushing syndrome?
small cell lung cancer
What cancer is associated with dermatomyositis?
lung CA
What cancer is associated with Down syndrome?
ALLL, AML
What cancer is associated with hypercalcemia?
squamous cell lung CA
What cancer is associated with lambert- eaton myastenic syndrome?
small cell lung cancer
What neoplasm is associated with myasthenia gravis and pure RBC aplasia?
thymoma
What neoplasm is associated with plummer vinson syndrome?
squamous cell carcinoma of the esophagus
What neloplasm is associated with polycythemia?
renal cell carcinoma, HCC
What cancers are associated with SIADH?
small cell lung CA
What cancers are associated with tuberous sclerosis (facial angiofibroma, seizures, intellectual disability)
giant cell astrocytoma, renal aniomyolipoma, cardia rhabdomyoma
What cancer is associated with APC mutations?
colorectal caner
this is a tumor suppressor
What is the significance of the tumor marker alkaline phosphatase?
mets to bone, liver, Paget disease of bone, seminoma (germ cell tumor of the testes)
What tumors make alpha fetal protein?
HCC, hepatoplastoma, yolk sac tumor, mixed germ cell tumor (co segreted with beta hCG in mixed)
What tumors may beta hCG
hydatidiform moles and choriocarcinomas. gestational trophoblastic disease
What is the significance of CEA?
carcinoembryonic antigen. very nonspecific but produced by 70% of colorectal and pancreatic cancers. also produced by gastric, breast, and medullar thryoid carcinomas
What is the significance of S-100?
secreted by cells of neural crest origin. think melanomas, neural tumors, schwannomas, langerhans cell histiocytosis
What is the significnce of TRAP
tartrate-resistant acid phosphatase. Made by hairy cell leukemia (B cell neoplasm)
