Neoplasms from first aid Flashcards

1
Q

What neoplasm is associated with acanthosis nigricans?

A

visceral malignancies, esp. stomach

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2
Q

What cancer is associated with actinic keratosis?

A

squamous cell carcinoma

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3
Q

What canceris associated with cushing syndrome?

A

small cell lung cancer

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4
Q

What cancer is associated with dermatomyositis?

A

lung CA

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5
Q

What cancer is associated with Down syndrome?

A

ALLL, AML

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6
Q

What cancer is associated with hypercalcemia?

A

squamous cell lung CA

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7
Q

What cancer is associated with lambert- eaton myastenic syndrome?

A

small cell lung cancer

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8
Q

What neoplasm is associated with myasthenia gravis and pure RBC aplasia?

A

thymoma

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9
Q

What neoplasm is associated with plummer vinson syndrome?

A

squamous cell carcinoma of the esophagus

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10
Q

What neloplasm is associated with polycythemia?

A

renal cell carcinoma, HCC

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11
Q

What cancers are associated with SIADH?

A

small cell lung CA

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12
Q

What cancers are associated with tuberous sclerosis (facial angiofibroma, seizures, intellectual disability)

A

giant cell astrocytoma, renal aniomyolipoma, cardia rhabdomyoma

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13
Q

What cancer is associated with APC mutations?

A

colorectal caner

this is a tumor suppressor

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14
Q

What is the significance of the tumor marker alkaline phosphatase?

A

mets to bone, liver, Paget disease of bone, seminoma (germ cell tumor of the testes)

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15
Q

What tumors make alpha fetal protein?

A

HCC, hepatoplastoma, yolk sac tumor, mixed germ cell tumor (co segreted with beta hCG in mixed)

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16
Q

What tumors may beta hCG

A

hydatidiform moles and choriocarcinomas. gestational trophoblastic disease

17
Q

What is the significance of CEA?

A

carcinoembryonic antigen. very nonspecific but produced by 70% of colorectal and pancreatic cancers. also produced by gastric, breast, and medullar thryoid carcinomas

18
Q

What is the significance of S-100?

A

secreted by cells of neural crest origin. think melanomas, neural tumors, schwannomas, langerhans cell histiocytosis

19
Q

What is the significnce of TRAP

A

tartrate-resistant acid phosphatase. Made by hairy cell leukemia (B cell neoplasm)