neoplasia III Flashcards

1
Q

tumor suppressors

A
Growth inh rec. TGFb
Growth signal transducers APC
Cell cycle regulators RB/E2F, p53, INK4A/p16
apoptosis Fas
DNA repair BRCA1 BRCA2
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2
Q

oncogene

A
Growth factors (e.g. FGF3)
GF receptors
GF signal transducers (Ras/abl)
Transcriptional activators (myc)
Cell cyc. regulators (cycD/cycE)

Survival signals

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