Neoplasia Flashcards
1
Q
Define neoplasia
A
abnormal tissue formation, whose growth exceeds and is un-coordinated as compared to noral tissue and which remains like that despite removal of the stimulus provoking the change
modern definition: a neoplastic cell has expanded clonally as a result of somatic mutations or other genetic alteration.
2
Q
Define carcinoma in situ
A
the entire epithelium is dysplastic, but there is NO invasion or metastasis.
3
Q
How to predict prognosis
A
Grading: degree of differentiation
Staging: Tumor size/location
4
Q
Grading of ductal adenocarcinoma is based on wat
A
Tubuli, mitoses, nuclear pleomorphism. Grading of ductal breast adenocarcinoma based.
5
Q
TNM staging is wat
A
T: tumor size and extent.
N: how many lymph nodes are involved
M: number of metastases.
