Neoplasia Flashcards

0
Q

What is a neoplasm?

A

Tumor mass

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1
Q

What is neoplasia?

A

Abnormal tissue mass with a loss of responsiveness to normal growth controls

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2
Q

What defines a benign lesion?

A

Relatively innocent; will remain localized and not spread; usually amenable to surgery; resemble parent tissue around it; will not usually penetrate the tissues around it

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3
Q

How do benign tumors cause damage?

A

Compression of normal tissue

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4
Q

metastasize (n.)

A

the spread of a neoplasm to a distant size where it will be locally invasive

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5
Q

How do metastases travel?

A

By the lymphatic system, through blood, and “seeding” within body cavities

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6
Q

Which two organs are the most frequent locations of metastases?

A

The lungs and the liver

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7
Q

oncology (n.)

A

the study, diagnosis, and treatment of tumors

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8
Q

What shape (generally) are metastases?

A

Circular/spherical

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9
Q

What does the suffix “-oma” mean?

A

Benign tumor

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10
Q

adenoma (n.)

A

benign tumor arising from glands or demonstrating glandular characteristics

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11
Q

What does the suffix “-carcinoma” mean?

A

Malignant tumor of epithelial origin

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12
Q

What does the suffix “-sarcoma” imply?

A

Malignant tumor of the mesenchyme

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13
Q

What does the suffix “-lymphoma” imply?

A

Solid tumors arising from lymphoid tissue

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14
Q

What type of malignant tumor is most common?

A

Carcinoma

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15
Q

What is mesenchymal tissue?

A

Connective tissue, muscle, bone, and cartilage

16
Q

leukemia (n.)

A

malignant cancer of hematopoietic stem cells - not a tumor

17
Q

What is anaplasia?

A

Poorly differentiated cancer tissue; hallmark of malignancy

18
Q

rhabdomyosarcoma (n.)

A

malignant muscle cell cancer (commonly referred to as RMS)

19
Q

myxoid tumor (n.)

A

connective tissue tumor with a “myxoid” background, consisting of a clear, mucoid substance

20
Q

What kinds of cancer do not metastasize?

A

Basal cell carcinomas of the skin and most CNS cancers

21
Q

What is the formula for tumor growth fraction (GF)?

A

of dividing cells / # of cells in the tissue

22
Q

What is the GF for a slow growing tumor?

A

10%

23
Q

What is the GF for a rapidly growing tumor?

A

20-30%

24
Q

iatrogenic (n.)

A

illness caused by medical examination or treatment