Final Flashcards
What are the three most common leukocytes involved in an inflammatory response?
Neutrophils, monocytes, and macrophages
What is the most common circulating leukocyte?
Neutrophil
Which is a more potent vasodilator: histamine or serotonin?
Serotonin (10,00 times more potent)
What are the derivatives of arachidonic acid?
Prostaglandins, thromboxanes, leukotrienes, lipoxins, and platelet-activating factor
What are the four main types of cytokines?
Interleukins, interferons, tumor necrosis factors, and growth factors
What is the first leukocyte to respond to inflammation?
Neutrophils
What is the second leukocyte?
Monocytes, which in tissue become macrophages
What is the factor number for the Hageman factor?
Clotting factor XII
What activates Hageman factor?
Bacterial endotoxins, BM/CT exposure, plasma and kallikrein
What is the main thing bradykinin causes?
Pain (ex. bee stings)
What types of cells are the hallmarks of chronic inflammation?
Macrophages/monocytes, lymphocytes (B & T cells), plasma cells, and eosinophils
What types of cells do you see in granulomatous inflammation?
Giant cells and macrophages
What two diseases do you see granulomatous inflammation in?
Tuberculosis and sarcoidosis (rare)
What drug would be less helpful in treating rheumatoid arthritis?
Acetaminophen
What cell type would you expect a deficiency in while seeing constant fungal, viral, and yeast infections?
T-cell lymphocytes
