Necrotizing Fasciitis Flashcards
1
Q
NF etiological agents
A
- Streptococcus pyogenes
- Staphylococcus aureus
- Clostridium
- Polymicrobial
2
Q
NF Empiric Therapy options
A
Scheme: Cover MRSA + Gram negatives + Anaerobes
1. Vancomycin + Piperacillin/Tazobactam
2. Vancomycin + Carbapenem
3. Vancomycin + Cefepime + Metronidazole/Clindamycin
4. Vancomycin + Ciprofloxacin + Metronidazole/Clindamycin
3
Q
What is typically added to NF therapy to inhibit toxin and cytokine production?
A
Clindamycin 900 mg IV q8hr