Necrotizing Fasciitis Flashcards

1
Q

NF etiological agents

A
  1. Streptococcus pyogenes
  2. Staphylococcus aureus
  3. Clostridium
  4. Polymicrobial
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2
Q

NF Empiric Therapy options

A

Scheme: Cover MRSA + Gram negatives + Anaerobes
1. Vancomycin + Piperacillin/Tazobactam
2. Vancomycin + Carbapenem
3. Vancomycin + Cefepime + Metronidazole/Clindamycin
4. Vancomycin + Ciprofloxacin + Metronidazole/Clindamycin

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3
Q

What is typically added to NF therapy to inhibit toxin and cytokine production?

A

Clindamycin 900 mg IV q8hr

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