NBME 12

Question 1

When is tactile fremitus increased?

Answer 1

consolidation (e.g. pneumonia, pulmonary edema, tumor)

Question 2

When is tactile fremitus decreased?

Answer 2

Pleural effusion or increased air in the lungs (e.g. obstructive lung disease, atelectasis, pneumothorax)

Question 3

What kind of HIV drug is indinavir?

Answer 3

protease inhibitor

Question 4

Ehich HIV drugs are protease inhibitors?

Answer 4

-navir

“NAVIR TEASE a proTEASE”

Question 5

What type of HIV drug is efavirenz?

Answer 5

NNRTI

Question 6

What kind of HIV drug is Raltegravir?

Answer 6

inTEGRAse inhibitor

Question 7

What is the difference between Zileuton and the -lukasts “zafirlukast and montelukast)?

Answer 7

Zileuton - LOX inhibitor

-lukasts - LT receptor inhibitors

Question 8

Bromocriptine’s MOA?

Answer 8

dopamine receptor agonist

Question 9

Phosphorylation of an enzyme most frequently occurs at which aa residues?

Answer 9

Serine and Threonine

Question 10

What are the most common side effects of statins?

Answer 10

Hepatotoxicity and rhabdomyolisis

Question 11

What is the role of Bcl-2?

Answer 11

anti-apoptotic

Question 12

What cells accumulate in abnormally high quantities in the alveoli and pulmonary interstitium in sarcoidosis?

Answer 12

CD4+

Question 13

Why don’t we have a GAS vaccine?

Answer 13

Antigens are too similar to human tissue!