natural toxins Flashcards

1
Q

What is the difference between opportunistic pathogens and frank (true) pathogens?

A

Opportunistic pathogens do not cause disease in a healthy individual.

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2
Q

Is it true that exotoxins are bacterial proteins?

A

true

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3
Q

What is endotoxins composition?

A

Lipopolysaccharides (LPS)

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4
Q

What is more toxic- exotoxins or endotoxins?

A

exotoxins

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5
Q

What are toxoid vaccines?

A

They neutralize the toxic activity created by bacteria.

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6
Q

What are the symptoms of SEB (Staphylococcal enterotoxin B) exposure?
What bacteria causes it?

A

the symptoms are similar to normal flu, chills, headache, sore throat and muscle pain.
Staphylococus aureus.

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7
Q

What is Common contributor to food poisoning in humans (mayonnaise products, eggs,
confectionery?

A

staphylococcal enterotoxicosis

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8
Q

When toxigenicity of diphtheria toxin occurs?
This toxin is produces by which bacteria?

A

occurs only when the bacillus is itself infected by a specific
virus carrying the genetic information for the toxin
Its produces by Corynebacterium diphtheriae

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9
Q

Name 3 toxins?

A

diphtheria toxin,
botulinum toxin,
SEB (Staphylococcal enterotoxin B)

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10
Q

What toxin has the biggest toxicity to the nervous system? Which bacteria produces it?

A

Botulinum toxin (Clostridium botulinum) -Block nerve functions and can lead to respiratory and muscular paralysis

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11
Q

How can a person be infected by Clostridium tetani? How is its released toxin called?

A

it enters body through wound;
tetanospasmin- binds in central nervous system, Leads to muscle spasm.

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12
Q

Name 2 neurotoxins?

A

tetanospasmin,
botulinum toxin (has biggest toxicity)

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13
Q

What is Shiga toxin?

A

Its produced by Escherichia coli, causes gastrointestinal disease.

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14
Q

How can we get intoxicated by cyanotoxins (produced by cyanobacteria)?

A

by touching or swimming in contaminated water (skin, eyes, throat irritation)

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15
Q

What are mycotoxins? How are they toxic?

A

toxins produced by filamentous fungi (molds) growing on crops, grains, fruits in the fields or can appear during storage.

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16
Q

How can a person get ergot poisoning?

A

When contaminated grains or foods made from them are consumed, the toxic alkaloids can cause neurological, gastrointestinal and blood vessel symptoms.

17
Q

What is the most common group of mycotoxins?

A

aflatoxins

18
Q

Are ergots mycotoxins?

A

yes they are

19
Q

What are common toxic effects of Poisonous mushrooms?

A

inflammation of the stomach and intestines,
hallucinations
liver toxicity

20
Q

What is one of the most poisonous mushrooms in the world?

A

Death cap

21
Q

What are the symptoms of poisoning of atropine?

A

dizziness, disorientation,
sometimes aggression
hallucinations
*Death due to failure of respiratory centre (a group of neural structures located in the brainstem responsible for regulating breathing)

22
Q

Which toxin is considered to be a ribosomal venom? What can it cause? How it can be exposed to human?

A

ricin, it blocks ribosomes physiological function.
Causes gastroenteritis, liver, kidney
and spleen damage (bluznis), death
Through: inhalation (powders), injections, mist or spray, contaminated food/water.

23
Q

From what animals we can get intoxicated?

A

insects, snakes