Narcotic Agonist-antagonist

Question 1

Action

Answer 1

• acts @ specific opioid receptor sites in the CNS but block other such receptors
• produces analgesia, sedation & a sense of well-being

Question 2

Uses

Answer 2

• relief of moderrate to severe pain
• adjuncts to general anesthesia
• relief of pain during labor & delivery

Question 3

Ex

Answer 3

nalbuphine (Nubain)

pentazocine (Talwin)

Question 4

Pharmacokinetics

Answer 4

-readily absorbed after IM admin

Question 5

Cautions

Answer 5

• resp dysfunction
• Myocardial infarction (MI) or Coronary artery disease (CAD)
• avoid driving, making important decisions and giving consent

Question 6

Drug-drug interactions

Answer 6

barbiturate
phenothiazines
MAOIs