Naphthalene Flashcards
Naphthalene is in the “old fashioned mothballs”.What is the name of the newer compound used in mothballs?
Paradichlorobenzene
When using a salt test to determine if a mothball contains naphthalene or paradichlorobenzene, the naphthalene mothball will ___ and the paradichlorobenzene will ___.
Naphthalene will rise and paradichlorobenzene will sink.
Cats are more sensitive to naphthalene but dogs are more susceptible. What is the lowest canine lethal dose?
~400mg/kg.
What are the routes of absorption of naphthalene?
Oral, inhalation, and intact skin.
Oil increases skin absorption.
What does the oxidation products of naphthalene cause?
Methemoglobinemia and hemolysis.
WHICH OF THE FOLLOWING FINDINGS WOULD MAKE YOU THE LEAST WORRIED ABOUT THE RISK OF RENAL FAILURE?
A. HEMATURIA
B. HEMOGLOBINURIA
C. MYOGLOBINURIA
THE ANSWER IS A, HEMATURIA.
Which form of iron in Hgb does not bind O2 leading to tissue hypoxia?
Ferric Fe3+
All of the following are CS of naphthalene toxicity except: A. Cataracts in geriatrics B. Mothball breath C. Salivation and vomiting D. Liver and kidney injury
A is not true. Cataracts can occur in the neonate.
Hemolysis, hemoglobinuria, and Heinz bodies can give you a definitive dx for naphthalene toxicity.
Don’t be silly, of course not! You have to rule out other causes of RBC oxidative injury. Such as, acetaminophen, onions, and nitrates.
Specific treatments for naphthalene toxicity are ____ _____ and _____ ___ _.
Ascorbic acid and Methylene blue 1%
T/F.
Ascorbic acid non-enzymatically converts MetHgb to Hgb and works relatively quickly.
False. It works slowly, not quickly. The rest is true.
Prognosis for naphthalene toxicity is…
A. So good you don’t even need to worry.
B. Reasonable.
C. Poor. Poor. Poor. Bad.
B. Reasonable if treated promply
How would giving sodium bicarb help with naphthalene toxicity?
It can reduce the precipitation of Hgb in the kidneys.
