Misc. Flashcards
In mammals, toxicity amount is described using…
LD 50 in mg/kg BW.
In birds, toxicity amount is described using…
LC50 mg/kg feed.
In fish, toxicity amount is described using…
LC50 mg/L H2O.
Acute toxicity occurs in what time frame?
24 hours.
Subacute toxicity occurs within what time frame?
1-30 days.
Subchronic toxicity occurs between what time frame?
30-90 days.
Chronic toxicity would be described as occurring over what amount of time?
3 months or more.
What is chronicity factor?
It is the ratio between acute LD50 and chronic LD50.
Extremely toxic = ?
1mg/kg or less.
Highly toxic = ?
1 - 50mg/kg.
Moderately toxic = ?
50 - 500mg/kg.
Slightly toxic = ?
0.5 - 5g/kg
Practically non-toxic = ?
5 - 15 g/kg.
Relatively harmless = ?
> 15g/kg
What is the highest/largest dose which does not result in undesirable or toxic alterations?
Highest non-toxic dose (HNTD)