Naltrexone Dosing (Stahl)

Question 1

Contraindicated:

Answer 1

Hepatitis or liver failure

Currently dependent on Opioids

Allergy

Currently in withdrawal

Taking some type of opioids for pain meds - FDA says not so

Question 2

Typical dosage for Alcohol usage

Answer 2

50 mg/day

100 mg - Monday
150 mg - Wed
150 mg - Friday

You do NOT need to titrate

Question 3

How long should patients be opioid free prior to the usage of Naltrexone

Short acting Opioid

Answer 3

5 days

Should be validated by Drug screen

Question 4

How long should patients be opioid free prior to the usage of Naltrexone

Long acting opioid

Answer 4

7 days

Question 5

Dose range for injection of Naltrexone

It is the same for alcohol and opioid dependency

Answer 5

380 mg/ monthly

Question 6

How often should you get your naltrexone injection

Answer 6

Monthly

Question 7

Naltrexone dose for Opioid addiction

Initial

Answer 7

25 mg

Question 8

When to titrate up Naltroxene dosage for opioid addiction

Answer 8

day 2

Titrate by 25 mg and stop at 50 mg/daily

Question 9

How long should we educate patient to abstain from alcohol before initiaton of naltroxene

Answer 9

At least 7 days

Shown to have greater reduction in the number of drinking days, abstain longer on tx

Question 10

How to stop?

Do we need to taper

Answer 10

A taper is not neccesary. We can just d/c whenever.