Naltrexone Flashcards
1
Q
MOA?
A
mu receptor and beta endorphin pathway antagonist preventing dopamine release in reward centre
2
Q
Uses?
A
1) heroin cessation
2) reduce alcohol cravings and consumption
3
Q
Contraindication?
A
Liver failure (Childs-Pugh ≥ B) ensuring that LFTs a recent
4
Q
What monitoring is required?
A
LFTs monthly for 3 months and 3 monthly thereafter
