Baclofen Flashcards
1
Q
MOA?
A
GABA-b agonist and also acts as an inhibitory neurotransmitter
2
Q
Contraindications?
A
poor renal function
3
Q
Half life?
A
2 - 4 hours so requires frequent administration
4
Q
Be wary of?
A
Acute withdrawal on discontinuation after prolonged used regardless of doses use (≥ 2 months) - similar to benzodiazepine withdrawal
5
Q
What can occur in overdose?
A
Seizures
6
Q
is it useful for alcohol dependance management and why?
A
No due to insufficient supporting evidence
