NaCl & urea Flashcards
What is the effect of water dissolution on NaCl toxicity ?
When NaCl dissolved in water = enhance toxicity.
In permanent water deprivation, toxic dose = lower than in appropriate water intake v(1à-20x daily needs).
Where is found the Na in the body ?
Extra-cellular
Which organ is mainly involved in the NaCl ecxretion ?
Kidneys
Which consequences appear in the case of a NaCl poisoning ?
Brain edema
Polyuria (if water available)
Nervous systM excitation & convulsions
Main CS in NaCl poisoning
Behavioural pb
Mvmt disorders
Autonomic signs
Eosinophilic brain infiltration + edema
Is there a specific ttt for NaCl poisoning ? If yes, which one ?
No spe ttt - sympto
Which specie is the most sensitive to urea poisoning ?
Ru = urease sensitive > H > other monogastrics = not sensitive
What does influ Urea absorption in the body ?
pH (<10 = NH3)
Which cycle is implied in urea detoxification ?
Citrate cycle
alpha-ketoglutaric acid
Urea mecha
Inhibit citrate cycle
Metabo alkalosis
Ion imbalance
What are the characteristic signs of urea poisoning ?
Bloat & ammonia odor
+ lung edema & hemo
+ liver dystrophy
Which substance can be used to counteract the urea poisoning ?
5% vinegar & cold water
+ glutamic acid to fix ammonia
Bloating & ammonia odor are characteritics from :
Urea poisoning