NaCl & urea Flashcards

1
Q

What is the effect of water dissolution on NaCl toxicity ?

A

When NaCl dissolved in water = enhance toxicity.
In permanent water deprivation, toxic dose = lower than in appropriate water intake v(1à-20x daily needs).

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2
Q

Where is found the Na in the body ?

A

Extra-cellular

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3
Q

Which organ is mainly involved in the NaCl ecxretion ?

A

Kidneys

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4
Q

Which consequences appear in the case of a NaCl poisoning ?

A

Brain edema
Polyuria (if water available)
Nervous systM excitation & convulsions

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5
Q

Main CS in NaCl poisoning

A

Behavioural pb
Mvmt disorders
Autonomic signs
Eosinophilic brain infiltration + edema

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6
Q

Is there a specific ttt for NaCl poisoning ? If yes, which one ?

A

No spe ttt - sympto

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7
Q

Which specie is the most sensitive to urea poisoning ?

A

Ru = urease sensitive > H > other monogastrics = not sensitive

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8
Q

What does influ Urea absorption in the body ?

A

pH (<10 = NH3)

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9
Q

Which cycle is implied in urea detoxification ?

A

Citrate cycle
alpha-ketoglutaric acid

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10
Q

Urea mecha

A

Inhibit citrate cycle
Metabo alkalosis
Ion imbalance

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11
Q
A
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12
Q

What are the characteristic signs of urea poisoning ?

A

Bloat & ammonia odor
+ lung edema & hemo
+ liver dystrophy

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13
Q

Which substance can be used to counteract the urea poisoning ?

A

5% vinegar & cold water
+ glutamic acid to fix ammonia

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14
Q

Bloating & ammonia odor are characteritics from :

A

Urea poisoning

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