Fluoride Flashcards
1
Q
Which spe is the most sensitive to Fluoride poisoning ?
A
Ru > P & poultry
2
Q
How is the absoprtion when the F is asso w/ Ca ?
A
Reduced
3
Q
Where does the F accumulate ?
A
In bone & teeth
4
Q
Action mecha of F :
A
HypoCa, high capillary permeability & inhibit enz
+ teratogenic
Bone & teeth -> OH –> hydroxyapatite
abn osteoblast mineralization
enz inhibition
Thyroid pb
5
Q
Acute F poisoning CS :
A
GI & hypoCa signs
6
Q
Chronic F poisoning CS :
A
bony alterations
teeth disturbances (dental lesions, mottled / Br enamel)
malnutrition
7
Q
Is there a spe ttt in F poisoning ? If yes, which one ?
A
Yes, ionized Ca in acute cases
Chronic = no spe ttt
