Mercury

Question 1

Which are the possible form of the Hg ?

Answer 1

Elemental / orga / inorga

Question 2

Which is the most toxic form of Hg ?

Answer 2

Elemental > alkyl > aryl (better absorbed) > inorga

Question 3

Where does Hg vapour accumulate ?

Answer 3

Lung -> RBC

Question 4

Is Hg2+ liposoluble / hydrosoluble ? Where does it accumulate ?

Answer 4

Liposoluble - CNS

Question 5

Inorga Hg form accumulates in (+elim) :

Answer 5

GI & skin absoprtion = low
Liver & kidney - elim = urine, saliva / intest gl = slow

Question 6

Orga Hg accumulates (elim) in :

Answer 6

GI, skin absorption = good - aryl = kidney / alkyl = CNS
Elim = liver, 90% re-circ

Question 7

Main CS in Hg poisoning :

Answer 7

Kidney damage / failure, oral muc necro, CNS damage

Question 8

Spe antidote in Hg poisoning ? If yes, which one ?

Answer 8

Yes in inorga form, Dimercaprol, Succimer, D-penicillamin & Na2S203
No spe ttt in orga form - irreversible brain lesions