Lead Flashcards

1
Q
A
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2
Q

How is the absorption for the inorga / orga Pb ?

A

Inorga = slow / incomplete
Orga = liposoluble, better GI & skin absorption

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3
Q

Pb distribution in the body ?

A

Liver -> entero-hepatic recirc

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4
Q

Which metals is accumulating in bony & hairy matter ?

A

Pb

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5
Q

Pb action mecha :

A

SH binding enz prot & heme / ATP synth inhibition
Neurotoxic effect
Liver / kidney degeneration, growth depression, abortion, GI muc necro

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6
Q

Main Pb poisoning CS :

A

Encephalopathy, GI malfunction

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7
Q

Which diagnostic method is used to highlight Pb poisoning ?

A

Delta-aminlevulinic acid in urine
Blood/ tissue Pb levels

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8
Q
A
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9
Q

Spe antidote in Pb poisoning ? If yes, which one ?

A

CaNa2-EDTA

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