n368_pharmacology_final_review_drugs_20140817171455 Flashcards

Question

Tetracycline, name the drug SEs?

Answer 1

super infections, nausea

Answer 2

phototoxicity, hepatoxicity

Answer 3

allergic reaction (rash, fever) diarrhea

Answer 4

allergic reaction (rash, fever) diarrhea

Answer 5

nausea, abdominal cramping, Most severe is hepatotoxicity

Answer 6

otoxicity and nephrotoxicity

Answer 7

Chlamydia; skin infections, acne

Answer 8

Inc. BP, rebound congestion, anxiety,Narrow angle glaucomaContraindication to patients with acute pancreatitis, heart disease, narrow-angle glaucoma

Answer 9

transient nasal irritation, burning, sneezing, or dryness, headache, rebound congestion - topical/nasal spray

Answer 10

Headache, dizziness, tremor, nervousness, throat irritation, tachycardia

Answer 11

Headache, dizziness, tremor, nervousness, throat irritation, tachycardia

Answer 12

Anticholinergic SE- transient nasal irritation, burning, sneezing, dryness, headache

Answer 13

__Nausea, vomiting, CNS stimulation (nervousness, tremors); narrow margin of safety

Answer 14

hypertension, hepatotoxicity, nephrotoxicity, reduction in urine flow

Answer 15

Flatulence, diarrhea, nausea, anorexia,

Answer 16

hypoglycemia, hepatoxicity, and weight gain

Answer 17

hepatoxicity (check liver enzymes), CHF, increased fluid retention

Answer 18

fluid and electrolyte imbalance; hyperkalemia that can lead to dysrhythmia

Answer 19

anaphylaxis; cardiac arrest, V fib

Answer 20

anticholinesterase agents toxicity; e.g. if someone has tardive dyskinesia use atropine to reverse

Answer 21

schizophrenia

Answer 22

Hyperlipidemia

Answer 23

CHF, HTN, Edema

Answer 24

HTN, angina

Answer 25

Secondary HTN

Answer 26

renal failure

Answer 27

reduce ICP (intracranial Pressure)

Answer 28

CHF, HTN, Edema

Answer 29

fungal infections

Answer 30

G(-) bacteria

Answer 31

G(-) bacteria

Answer 32

Tx for chlamydi; G (+) G(-) bacteria

Answer 33

Effective against G(+); G(-) organisms ophthalmic infections, sinusitis, and prostatitis

Answer 34

G (+), gonorrhea and syphilis

Answer 35

H.flu or M. catarrhalis

Answer 36

H. pylori (peptic ulcers) and Whooping cough, Gram (-)

Answer 37

superinfections, nausea

Answer 38

Allergic rhinitis and common cold

Answer 39

Allergic rhinitis and common cold

Answer 40

asthma & pulm. Disorders

Answer 41

asthma & pulm. Disorders

Answer 42

asthma & pulm. Disorders

Answer 43

chronic asthma & COPD

Answer 44

prevention of organ rejection

Answer 45

oral antidiabetic

Answer 46

oral antidiabetic

Answer 47

DM Type II

Answer 48

HTN; CHF; Ascites from liver disease

Answer 49

Bind GABA channel, hence GABA Agonist (i.e. mimics GABA's inhibitory effect)

Answer 50

antagonizes opioid effect

Answer 51

stimulates alpha and beta adrenergic receptors

Answer 52

competitively inhibits benzo receptor site

Answer 53

antagonist of muscarinic Ach receptors

Answer 54

Blocking D2-Dopamine receptor

Answer 55

Interfere with HMG-CoA reductase, the critical enzyme in the biosynthesis of cholesterol

Answer 56

Act on ascending limb of the loop of Henle to block the reabsorption of sodium and water.

Answer 57

Antihypertensive; act on the early distal tubule to block the reabsorption of sodium, chloride, and water; Excretion of potassium is increased.

Answer 58

blocks beta adrenergic receptors

Answer 59

block calcium ion channels in arterial smooth muscles, causing vasodilation and decrease heart contractility

Answer 60

inhibit sympathetic activation of arterioles thereby causing vasodilation

Answer 61

block calcium ion channels in arterial smooth muscles, causing vasodilation and decrease heart contractility

Answer 62

decrease cardiac workload by slowing HR

Answer 63

Antihypertensive; block formation of angiotensin II, causing vasodilation, and block aldosterone secretion, decreasing fluid volume

Answer 64

decrease the cardiac afterload by dilating vessels and reducing preload

Answer 65

Used to improve cardiac function; decrease cardiac workload by slowing the HR (beta-1 effect )and decreasing blood pressure (alph1-effect: carvedilol)

Answer 66

Inotropics;Increase cardiac output by increasing the force of myocardial contraction

Answer 67

inhibit carbonic anhydrase from making carbonic acid from CO2 and water, hence more water & CO2 ouput; decrease volume

Answer 68

increase osmotic pressure of glomerular filtrate thereby inhibit reabsorption of water

Answer 69

Act on ascending limb of the loop of Henle to block the reabsorption of sodium and water.

Answer 70

changes permeability in membrane leading to cell death

Answer 71

inhibit bacteria protein synthesis

Answer 72

inhibit bacteria protein synthesis

Answer 73

inhibit bacterial protein synthesis, slowsuperinfections, nauseatetracycline HCL (Achromycin, others)__

Answer 74

to inhibit bacterial DNA gyrase ,Affects bacterial replication and DNA repair,Effective against G(+); G(-) organism

Answer 75

mechanism action N/A

Answer 76

kill bacteria by disrupting their cell walls and allowing water to enter

Answer 77

clavulanate inhibits betalactamase destruction by bacteria allowing amoxicillin to work by disrupting cell wall

Answer 78

inhibit protein synthesis by binding to bacterial ribosome

Answer 79

inhibits cells wall biosynth. Increase permeability of cell membrane

Answer 80

inhibit bacterial protein synthesis, slowsuperinfections, nauseatetracycline HCL (Achromycin, others)

Answer 81

alpha 1 agonist

Answer 82

vasconstricts vessels in nasal tissues

Answer 83

binds to beta 2 receptors causing bronchodilation

Answer 84

binds to beta 2 receptors causing bronchodilation

Answer 85

blocks PNS (rest and digest), thereby blocking bronchoconstriction and resulting in bronchodilation

Answer 86

inhibition of isozymes

Answer 87

Immunosuppressant; Bind to calcineurin, an intracellular messenger, and disrupt T cells

Answer 88

decreases hepatic production of glucose

Answer 89

increase insulin secretion from pancreas; increase

Answer 90

decr insulin resistance;

Answer 91

acts on late distal tubule blocking sodium, but retain potassium

Answer 92

Benzodiazepine

Answer 93

opioid antidote

Answer 94

adrenergic

Answer 95

GABA antagonist; benzo antidote

Answer 96

anticholinergic

Answer 97

typical antipsychotic

Answer 98

statin (HMG-Co A1 reductase inhibitor))

Answer 99

Loop diuretic, anti-HTN

Answer 100

Diuretic; thiazide

Answer 101

Beta Blocker (aka beta antagonist)

Answer 102

CCB, anti-HTN

Answer 103

Alpha-1 adrenergic antagonist; ant-HTN

Answer 104

anti-HTN, Beta Blocker (aka beta antagonist)

Answer 105

ACE Inhibitor

Answer 106

Direct Vasodilator

Answer 107

Beta Blocker & Alpha 1 selective blocker

Answer 108

cardiac glycoside; inotropic

Answer 109

Diuretic; Carbonic Anhydrase Inhibitor

Answer 110

Osmotic Diuretic

Answer 111

Loop diuretic, anti-HTN

Answer 112

antifungal

Answer 113

antibiotic, bactericidal; broad spectrum

Answer 114

antibiotic, bactericidal; broad spectrum

Answer 115

antibiotic, broad spectrum, bacteriostatic

Answer 116

antibiotic (broad spectrum); bactericidal

Answer 117

metronidazole, antibiotic

Answer 118

aminopenicillin; bactericidal

Answer 119

bactericidal, aminopenicllin and betalactamase inhibitor combination

Answer 120

Macrolide, antibiotic

Answer 121

vancomycin (its own class), bactericidal, antibiotic

Answer 122

tetracycline, antibiotic, bacteriostatic

Answer 123

Decongestant

Answer 124

Decongestant

Answer 125

Bronchodilators

Answer 126

Bronchodilators

Answer 127

Bronchodilators; anticholinergic

Answer 128

Bronchodilators

Answer 129

Calcineurin inhibitors (i.e., CYCLOSPORIN)

Answer 130

Biguinide; oral antidiabetic

Answer 131

second gen sulfonylurea

Answer 132

oral antidiabetic, glitazone

Answer 133

Diuretic; potassium-sparing antidiuretic