N368 Test 2 Drugs Affecting the ANS Flashcards
adrenergic agonists
stimulate that sympathetic nervous system
adrenergic antagonists
inhibit the stimulation of the sypatheic nervous system
cholinergics
stimulate the parasympathetic nervous system
anticholingerics
inhibit the parasympathetic nervous system
Drugs that stimulate that SNS result in a _____ response
fight ot flight
term given to the parasympathetic nervous system
break pedal
Drugs that stimulate the SNS are called
adrenergics
adrenergic agonists
sympathomimetics
Neurotransmitters for SNS
Epinephrine
Norepinephrine
Dopamine
Exmaples of synthetic neurotransmitters for the SNS
Isuprel and dobutamine
What type of response do Isuprel and dobutamine produce and when are they used?
Sympathomimetic
intense cardiac agents used in shock
Beta 1 Receptor Site
Heart
Beta 2 Receptor Site
bronchiole walls
Alpha 1 Receptor Site
Urinary bladder and ciliary muscle of the cyes
Alpha 2 Receptor Site
GI tract
Alpha 1Stimulation Response
increases force of contractions, increased BP, dialates pupils, decreases salivation, bladder relaxation with urinary sphincter contractions
Alpha 2 Stimulation Response
vasodialation, decrease GI motility and tone, reduces NE release
Beta 1 Stimulation Response
increase BP, increase myocardial contractility, increase renin release, increases oxygen supply to myocardial tissue, has a cardio protective effect
Beta 2 Stimulation Response
bronchodilation, GI relaxation, uterine relaxation, increased blood sugar, blood flow to skeletal muscle
what is renin
a precursor to vasoconstriction
nonselective adrenergic agents:
stimulate more than one receptor site in equal proportions, leading to more side effects
selective adrenergic agents:
have greater affinity for certian receptors
Alpha 1 Sympathomimetic applications
hypotension, mydriasis (eye exams), nasal congestion
Alpha 2 Sympathomimetic applications
hypertension
Beta 1 Sympathomimetic applications
cardiac arrest, heart failure, and shock
Beta 2 Sympathmomimetic applications
asthma, premature labor
synthetic version of epinephrine
adrenalin
What receptor sites are effected by ephinephrine
Alpha, Beta 1 and Beta 2
Through what routes can epinephrine be given
most commonly given through IV but can also be given through IM, SQ, and Inhalation
What are some situations in which epinephrine would be used
anaphylactic shock, bronchial spasms, cardiac arrest, severe allergic reactions
Side effects of epinephrine
anorexia, N&V, nervousness, agitation, headache, insomnia, syncope, dizziness
What is the synthetic name for norepinephrine
levophed
In what situation might norepinephrine be used?
cardiac shock
What response does norepinephrine have
vasoconstrictor, increases BP and CO
Nursing assesment when giving norepinephrine
monitor BP q 2-5 minutes during infusion
catecholamines
naturally occurring neurotransmitters
What should be monitored when giving both Beta 2 agonist and antagonists
blood pressure and blood sugar
Why is epinephrine not usually given IM?
can cause muscular necrosis
What are the receptor sites for norepinephrine?
Alpha 1 and Beta 1
What is the synthetic version of Dopamine?
inotropin
What are the receptor sites for dopamine
Alpha 1 and Beta 1
What is the most common route for giving inotropin?
IV
Why is inotropin used?
to correct hypotension and increase cardiac contractility
What happens to the kidenys in with low doses of inotropin?
increase in renal blood flow
What happend to the kidney in high doses of inotropin?
blood flow is cut of to the kidneys
What should be assesed when giving inotropin
BP, urinary output, cardiac output
What is givin if the IV site becomes infiltrated when giving inotropin
Regitine SQ
What is the generic name for Dobutrex?
Dobutamine
What is the receptor site for dobutamine
Beta 1
What is dobutamine used for
cardiac shock
Through what route is dobutamine given?
IV
What is the result of a dobutamine infusion?
increased cardiac contractility, stroke volume, and cardiac output