Myocardial Infarction Flashcards

1
Q

What is MI

A
  • prolonged ischemia, injury and death of an area of the myocardium caused by occlusion of one or more of the coronary arteries
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2
Q

precipitating factors of MI

A
  • atherosclerotic heart disease with thrombus formation
  • coronary vasospasm
  • embolism
  • cocaine
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3
Q

What is a zone of infarction

A
  • consists of necrotic, noncontractile tissue
  • electrically inert
  • on ECG: ST segment deviation > 1mm
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4
Q

Zone of injury

A
  • area immediately adjacent to central zone
  • tissue is non contractile
  • cells under going metabolic changes
  • electrically unstable
  • On ECG: see elevated ST segments in leads of injured area
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5
Q

Zone of ischemia

A
  • outer area
  • cells also undergoing metabolic changes
  • electrically unstable
  • on ECG: T wave inversion
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6
Q

Transmural infarction site

A
  • full thickness of myocardium
  • often ST elevated MI - STEMI
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7
Q

Nontransmural infarction site

A
  • subendocardial, subepicardial, intramural infarctions
  • non-ST elevated MI - NSTEMI
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8
Q

Right coronary artery occlusion

A
  • inferior MI
  • right ventricle infarction
  • disturbances of upper conduction system
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9
Q

Circumflex artery occlusion

A

lateral MI
ventricular ectopy

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10
Q

left anterior descending artery occlusion

A

anterior MI
disturbances of lower conduction system

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11
Q

Impaired ventricular function results in

A
  • decreased stroke volume, CO, and EF
  • increased end diastolic ventricular pressures
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12
Q

electrical instability

A
  • arrhythmias
  • present in injury and ischemic areas
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13
Q

What is sudden death usually due to

A

significant ischemia or ventricular arrhythmia

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14
Q
A
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