Myelodysplastic Syndrome Flashcards

1
Q

Refractory Anaemia

A

RA

Anaemia

No Blasts

Erythroid Dysplasia with <5% blasts

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2
Q

Refractory Anaemia with Ring Sideroblasts

A

RA + RS

Anaemia

No Blasts

Ring sideroblasts

Erythroid dysplasia with >15% ringed sideroblasts
<5% blasts

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3
Q

Refractory cytopenia with multilineage dysplasia

A

RCMD

Cytopenia >/2 cell lines

Dysplasia in >10% cells in >/ cell lines

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4
Q

Refractory cytopenia with multilineage dysplasia and ringed sideroblasts

A

RCMD+RS

Cytopenia >/2 cell lines

Dysplasia in >10% cells in >/ cell lines
With >15% Ringed sideroblasts

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5
Q

Refractory anaemia with excess blasts 1

A

RAEB I

Cytopenias

<5% blasts in BLOOD
No auer rods

In Bone marrow: 5-9% blasts

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6
Q

Refractory anaemia with excess blasts 2

A

RAEB II

Cytopenias

5-19% blasts in BLOOD

Auer rods

In Bone marrow: 10-19% blasts / Auer rods

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7
Q

Myelodysplastic syndrome with isolated 5q deletion

A

Anaemia

Normal platelets

<5% blasts

Megakaryocytes with hypoblated nuclei

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8
Q

Myelodysplastic syndrome Unclassified

A

Complex

Cytopenias

No blasts

No Auer rods

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9
Q

RA

Anaemia

No Blasts

Erythroid Dysplasia with <5% blasts

A

Refractory Anaemia

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10
Q

RA + RS

Anaemia

No Blasts

Ring sideroblasts

Erythroid dysplasia with >15% ringed sideroblasts
<5% blasts

A

Refractory Anaemia with Ring Sideroblasts

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11
Q

RCMD

Cytopenia >/2 cell lines

Dysplasia in >10% cells in >/ cell lines

A

Refractory cytopenia with multilineage dysplasia

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12
Q

RCMD+RS

Cytopenia >/2 cell lines

Dysplasia in >10% cells in >/ cell lines
With >15% Ringed sideroblasts

A

Refractory cytopenia with multilineage dysplasia and ringed sideroblasts

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13
Q

RAEB I

Cytopenias

<5% blasts in BLOOD
No auer rods

In Bone marrow: 5-9% blasts

A

Refractory anaemia with excess blasts 1

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14
Q

RAEB II

Cytopenias

5-19% blasts in BLOOD

Auer rods

In Bone marrow: 10-19% blasts / Auer rods

A

Refractory anaemia with excess blasts 2

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15
Q

Anaemia

Normal platelets

<5% blasts

Megakaryocytes with hypoblated nuclei

A

Myelodysplastic syndrome with isolated 5q deletion

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16
Q

Complex

Cytopenias

No blasts

No Auer rods

A

Myelodysplastic syndrome Unclassified