Myelodysplastic Syndrome Flashcards
Refractory Anaemia
RA
Anaemia
No Blasts
Erythroid Dysplasia with <5% blasts
Refractory Anaemia with Ring Sideroblasts
RA + RS
Anaemia
No Blasts
Ring sideroblasts
Erythroid dysplasia with >15% ringed sideroblasts
<5% blasts
Refractory cytopenia with multilineage dysplasia
RCMD
Cytopenia >/2 cell lines
Dysplasia in >10% cells in >/ cell lines
Refractory cytopenia with multilineage dysplasia and ringed sideroblasts
RCMD+RS
Cytopenia >/2 cell lines
Dysplasia in >10% cells in >/ cell lines
With >15% Ringed sideroblasts
Refractory anaemia with excess blasts 1
RAEB I
Cytopenias
<5% blasts in BLOOD
No auer rods
In Bone marrow: 5-9% blasts
Refractory anaemia with excess blasts 2
RAEB II
Cytopenias
5-19% blasts in BLOOD
Auer rods
In Bone marrow: 10-19% blasts / Auer rods
Myelodysplastic syndrome with isolated 5q deletion
Anaemia
Normal platelets
<5% blasts
Megakaryocytes with hypoblated nuclei
Myelodysplastic syndrome Unclassified
Complex
Cytopenias
No blasts
No Auer rods
RA
Anaemia
No Blasts
Erythroid Dysplasia with <5% blasts
Refractory Anaemia
RA + RS
Anaemia
No Blasts
Ring sideroblasts
Erythroid dysplasia with >15% ringed sideroblasts
<5% blasts
Refractory Anaemia with Ring Sideroblasts
RCMD
Cytopenia >/2 cell lines
Dysplasia in >10% cells in >/ cell lines
Refractory cytopenia with multilineage dysplasia
RCMD+RS
Cytopenia >/2 cell lines
Dysplasia in >10% cells in >/ cell lines
With >15% Ringed sideroblasts
Refractory cytopenia with multilineage dysplasia and ringed sideroblasts
RAEB I
Cytopenias
<5% blasts in BLOOD
No auer rods
In Bone marrow: 5-9% blasts
Refractory anaemia with excess blasts 1
RAEB II
Cytopenias
5-19% blasts in BLOOD
Auer rods
In Bone marrow: 10-19% blasts / Auer rods
Refractory anaemia with excess blasts 2
Anaemia
Normal platelets
<5% blasts
Megakaryocytes with hypoblated nuclei
Myelodysplastic syndrome with isolated 5q deletion