Brain Tumours Flashcards

1
Q

Stage IV Automatic

A

Glioblastoma multiforme

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2
Q

Fried egg tumour

A

Oligodendroglioma

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3
Q

Piloid hairy cell

A

Pilocystic Astrocytomas

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4
Q

Necrotic core

A

Glioblatsoma multiforme

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5
Q

Progress to Glioblastoma multiforme

A

Diffuse Astrocytoma

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6
Q

Rosenthal fibres and granular bodies

A

Pilocystic adenomas

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7
Q

Prominent brain tumour in children

A

Medulloblastoma

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8
Q

30% contain calcification

A

Oligodendroglioma

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9
Q

According to the WHO criteria a grade III tumour causes death within

A

5 years

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10
Q

According to the WHO criteria a grade IV tumour causes death within

A

6m - 1 Year

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11
Q

Does not infiltrate

Compression

Encapsulated

A

Meningioma

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12
Q

cerebellar signs, cranial hypertension

A

Medulloblastoma

Grade IV

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13
Q

Mutation of IDH1 in 80% of cases.

A

Diffuse Astrocytomas

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14
Q

Pallisades: build up of cells to fence off necrotic tissue

A

Glioblastoma Multiforme

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15
Q

Chemosensitive

Better prognosis than astrocytomas – resection is important

80% mutation of IDH1; 75% codeletion 1p19q; usually normal p53

A

Oligodendroglioma

= fried egg tumour

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16
Q

WHO grade I

A

Pilocystic Astrocytoma

17
Q

Children – usually midline of vermis

Adult – usually hemispheric

A

Medulloblastoma

Vermis = midline of cerebellum

18
Q

Seizure, compression

A

Meningioma

19
Q

Glioblastoma multiforme

A

Stage IV Automatic

20
Q

Oligodendroglioma

A

Fried egg tumour

21
Q

Pilocystic Astrocytomas

A

Piloid hairy cell

22
Q

Glioblatsoma multiforme

A

Necrotic core

23
Q

Diffuse Astrocytoma

A

Progress to Glioblastoma multiforme

24
Q

Pilocystic adenomas

A

Rosenthal fibres and granular bodies

25
Q

Medulloblastoma

A

Prominent brain tumour in children

26
Q

Oligodendroglioma

A

30% contain calcification

27
Q

5 years

A

According to the WHO criteria a grade III tumour causes death within

28
Q

6m - 1 Year

A

According to the WHO criteria a grade IV tumour causes death within

29
Q

Meningioma

A

Does not infiltrate

Compression

Encapsulated

30
Q

Medulloblastoma

Grade IV

A

cerebellar signs, cranial hypertension

31
Q

Diffuse Astrocytomas

A

Mutation of IDH1 in 80% of cases.

32
Q

Glioblastoma Multiforme

A

Pallisades: build up of cells to fence off necrotic tissue

33
Q

Oligodendroglioma

= fried egg tumour

A

Chemosensitive

Better prognosis than astrocytomas – resection is important

80% mutation of IDH1; 75% codeletion 1p19q; usually normal p53

34
Q

Pilocystic Astrocytoma

A

WHO grade I

35
Q

Medulloblastoma

Vermis = midline of cerebellum

A

Children – usually midline of vermis

Adult – usually hemispheric

36
Q

Meningioma

A

Seizure, compression