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Microbio > Mycoses > Flashcards

Mycoses Flashcards

1
Q

Histoplasmosis

A

Missippi and Ohio River valleys

Bird/bat droppings (Spelunking)

Histo Hides in Macrophages

Self limited, inhaled

Causes pneumonia, but ability for it to go systemic/disseminate

Smaller than RBC

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2
Q

Missippi River Valley/ Ohio River Valley

A

Histoplasmosis

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3
Q

Spelunking

A

Histoplasmosis

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4
Q

Blastomycosis

A

East of Mississippi River and Central America

(pneumoniae) Inflammatory lung disease, disseminates to BONE and SKIN (like cocci)

Granulomatous nodules

Blast Buds Broadly. Same size as RBC

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5
Q

Central US

A

Blastomycosis

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6
Q

Within macrophages

A

Histoplasmosis (Histo Hides)

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7
Q

Same size as RBC

A

Blastomycosis (Broad budding)

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8
Q

Smaller than RBC

A

Histoplasmosis

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9
Q

Larger than RBC

A

Coccidioidomycosis

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10
Q

Coccidioidomycosis

A

SW US

Pneumonia, MENINGITIS

can disseminate to BONE and SKIN. Like blasto

Spherule > RBC

Desert bumps, erythema nodosum
Desert rheumatism, arthralgias

San Joaquin River Valley

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11
Q

Bone and Skin

A

Blasto or Coccidio

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12
Q

Spherule

A

Large w/ endospores (Coccidio)

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13
Q

Erythema nodosum

A

Coccidio

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14
Q

Paracoccidioidomycosis

A

Latin America

Budding year w/ Captains weal

Granuloma in skin or mucous

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15
Q

Meningitis

A

Coccidio

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16
Q

Malassezia furfur

A

Tinea Versicolor

Hypo or hyperpigmented patches.

Hot humid weather.

Degrades lipids and produces acid –> destroys melanocytes

Scalp = oral treatment

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17
Q

Tinea pedis

A

Athletes foot

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18
Q

Tinea Cruris

A

Groin fungal

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19
Q

Tinea corporis

A

Ring worm on body

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20
Q

Tinea capitis

A

Ring worm on scalp

21
Q

Tinea uniquium

A

Onychomycosis (usually trichophyton)

22
Q

Tinea

A

Pruritic lesion w/ central clearing

Trichophyton
Epidermophyton
Microsporum

Mold hyphae on KOH prep, not dimorpihic

23
Q

Trichophyton

A

Dermatophytes

24
Q

Epidermophyton

A

Dermatophytes

25
Q

Microsporum

A

Dermatophytes

26
Q

Malassezia furfur

A

Dermatophyte

27
Q

Esophageal/Oral thrush

A

Immunocompromized. Fluconazole/Caspofungin

28
Q

Vulvovaginitis

A

DM or Antibiotic threatment

29
Q

Diaper rash

A

Candida

30
Q

Endocarditic in IVDA

A

Candida

31
Q

Chronic mucocutaneous Candida

A

T cell deficiency

32
Q

Systemic Candida

A

Neutropenia

33
Q

Invassive aspergillosis

A

Immunocompromised or CGD

34
Q

Allergic Bronchopulmonary aspergillosis

A

Asthma and CF.

Cause Brochiectasis and Eosinophilia

35
Q

Aspergilloma

A

Lung cavity, often after TB

36
Q

Alfatoxin

A

HCC from Aspergillus

37
Q

Acute Angles

A

Aspergillus

38
Q

Paseudohyphae

A

Candida

39
Q

Pigeon Droppings/soil

A

Crypto,

COuld be histo too, or c. psitticae

40
Q

Soap Bubble Lesion in brain

A

Cypto

41
Q

India Ink

A

Cypto

42
Q

Cyptococcus

A

Meningitis in AIDS

Encapsulated yeast.
CSF or Serum for Dx.

Latex agglutinin test - Specific

43
Q

Latex Agglutination

A

Crypto

44
Q

Ketoacidotic Diabetic and Leukemia

A

Mucor or Rhizopus

45
Q

Mucor/rhizopus

A

Proliferate in vessel walls when excess ketone and glucose.

Enter brain + eye via cribiform

Rhinocerebral frontal lobe abcess,

Necrotic eschar

46
Q

PCP

A

Diffuse interstitial pneuonia

Yeast, inhaled.

Usually asymtpo

Immunosuppression progresses to disease

Diffuse bilat CXR

Dx: Lung biopsy/lavage

Disc shaped yeast on methenamine silver stain

47
Q

Yeast

A

Candida, Crypto, PCP

48
Q

Neutropenia

A

Apergillus or Candida

49
Q

Sporothrix

A

Dimorphic cigar shape yeast

Gardner’s disease (thorn)

Traumatically induced.

Local pustule/ulcer w/ nodules along draining lympahtics

Microbio (11 decks)

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