Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

bacteria > Mycoplasma > Flashcards

Mycoplasma Flashcards

1
Q

Mycoplasma general characteristics

A

No cell wall
evolved from Gram positive
pleiomorphic bacteria
difficult to manipulate in vitro

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Human pathogenic Mycoplasma

A 
M. pneumoniae
M. hominis
M. genitalium
M. fermentens
Ureaplasma urealyticum
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Mycoplasma unique requirement

A

Require cholesterol- cant make cholesterol so much get it from host

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Colony morphology of Mycoplasma

A

“fried egg” colony morpholoy

except M. pneumonia- round mulberry colony

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Virulence factors of Mycoplasma

A

Hemolysins (alpha and beta)
adherence to ciliated respiratory epithelial cells
polysaccharide Capsule
Toxins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What toxin does M. pneumoniae produce?

A

Community Acquired Respiratory Distress Syndrome (CARDS) toxin- ADP ribosylating and vacuolating toxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is unique about M. pneumonia (of all the bacteria that cause primary community acquired pneumonia)?

A

M. pneumonia is associated with the appearance of cold agglutinins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Disease of M. pneumonia

A

atypical community acquired pneumonia
dry cough, fever, scratchy throat
“walking pneumonia”
leading cause of pneumonia in school aged children and young adults

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

M. pneumoniae diagnosis

A

Serology

PCR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Immune response to M. pneumonia

A

early response; IgM
late response: IgG
IgA in respiratory secretion and cell mediated immunity play a role in resistance
short term immunity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are cold agglutinins and which bacteria is associated with it

A

M. pneumoniae
Cold agglutinins- IgM antibodies that agglutinate host RBCs at 4degC, not at at 37degC
during infection, some RBC antigens are damaged and not recognized as self anymore, and the host mounts a response against the RBC, Cold agglutinins represents a type of autoimmune response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Diganosis of M. pneumoniae

A

Serology: ELISA or latex agglutination assays for IgG and IgM
round mulberry colonies
B- hemolysis (M. pneumoniae have B-hemolysins)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Treatment of M. pneumoniae

A 
Doxycyclines
Ciprofloxin
Levofloxin
Erythromycin
Azithromycin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

M. Mycoplasma prevention

A

No vaccines- immunity is short lived (same reason as for chlamydia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Which Mycoplasma cause genital disease?

A

M. Hominis, M. genitalium, U. urealyticum
all members of normal flora- opportunistic pathogens
acquired through sexual contact

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

U. urealyticum is one of several agents that cause what?

A

non-gonococcal urethritis

17
Q

M. Fermentans and M. penetrans is associated with what?

A

HIV

HIV grow better in vitro if the host cells are already infected with M. fermentans or M. penetrans

bacteria (16 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions