Corynebacterium Flashcards
1
Q
most important species
A
Corynebacterium diphtheriae
2
Q
Morphology
A
Gram positive bacilli, aerobic, non-spore forming
3
Q
Virulence factor
A
Diphtheria toxin- ADP ribosylates EF2, inhibits protein synthesis
4
Q
Disease
A
acute respiratory infection with pseudomembrane formation in throat
progress to respiratory failure and death
5
Q
Treatment:
A
Antitoxin serum (from CDC) + erythromycin or penicillin
6
Q
Prevention
A
DTP vaccine
rare in US
