Mycoplasma Flashcards
Characteristics of Mycoplasma?
- Smallest free living organism
- NO PEPTIDOGLYCAN
- non motile
- NO CELL WALL
Mycoplasma pneumoniae is a classical cause of what?
“atypical” walking pneumonia
Frequent outbreaks of Mycoplasma seen where?
- Military recruits
- Prisons
Community acquired pneumonia outbreaks from Mycoplasma occur in whom?
young patients 5-15 years old
what is the most important adhesion factor located on tip of organelle in Mycoplasma?
P1 adhesion factor
attachment of Mycoplasma via tip organnele (P1) causes what?
cilia arrest/loss leading to epithelial cell necrosis
The cell membrane of mycoplasma resembles host because of what?
Because of Cholesterol, so it triggers auto-reactive antibodies
Mycoplasma is linked to what diseases/syndromes?
- Fibromyalgia
- Chronic fatigue
- Gulf War Syndrome
Mycoplasma is grown on what agar?
Eaton’s agar
What get chronic infection with Mycoplasma?
IL-12 –> Th1 –> CMI –> Hypersensitivity –> Chronic Infection
Treatment for Myplasma pneumoniae?
Erythromycin, but NO B-lactams
What appearance does Mycoplasma ave on Eaton’s agar?
Chol Fried egg colonies
This certain bacteria has Chol “fried egg” colonies on Eaton’s agar. What diagnostic test could you do for this bacteria?
Cold Agglutinin Test
Mycoplasma
