Mycology

Question 1

Fungal cell wall

Answer 1

virulence factor

target of antifungal drugs

Question 2

yeast reproduce by

Answer 2

budding

Question 3

aspergillus

Answer 3

aflatoxin
inhalation of aspergillus condida can cause disease
melanin=cell wall pigment that can interfere with phagocytosis

Question 4

Crytococcus neoformans

Answer 4

pigeon droppings as vector
crytococcal meningitis
polysaccharide capsule=virulence factor

Question 5

Candida albicans

Answer 5

hyphae grow into tissue

have proteases that can destroy host proteins

Question 6

Sporothrix schenckii

Answer 6

rose gardener’s disease

can get from a thorn prick

Question 7

Histoplasmosis

Answer 7

“cave disease”
often associated with decaying bat guano or bird droppings
dimorph causes disease

Question 8

Coccidiodomycosis

Answer 8

valley fever-SW US

Question 9

Azoles

Answer 9

inhibition of ergosterol synthesis (cell wall)

Question 10

Polyenes

Answer 10

direct cell memb damage (bird to erg)

Question 11

Flucytosine

Answer 11

inhibit nucleic acid synthesis

Question 12

Echinocandins

Answer 12

inhibit glycan synthesis