Mycology

Question 1

What are some typical unicellular eukaryotic cells

Answer 1

Yeast that are

• Facultive anaerobes
• Asexual reproduction
• Can grow on agar

Question 2

What are some typical moulds

Answer 2

Filametous that are

• Aerobes
• Asexual spores known as Aonidia
• Produce Mycelia (branchingthread like hyphae)

Question 3

Different types of Virulent Fungii

Answer 3

Dimorphic Fungi, Dermatophytes, subcutaneous mycoses, oppurtunistic and toxic fungi

Question 4

What organisms make up dermatophytes

Answer 4

Microsporum, Trichophyton, Epidermopyton and they can cause tinea

Question 5

Examples of Subcutaenous mycoses

Answer 5

Mycetoma, Chromoblastomycosis and Phaeohyphomycosis

Question 6

Different organisms that cause mycetoma (Maduromycosis)

Answer 6

Bacterial (acintomycetoma) eg Nocardia spp

Fungal (eumycetoma) eg Madurella

Question 7

Opportunistic Mycoses

Answer 7

Candida albicans, Cryptococcis, Aspergillosis

Question 8

Organisms that cause crytococcis

Answer 8

C. neoformans and C. gattii and is an AIDS defining illness

Question 9

Dimorphic Fungi

Answer 9

Histoplasma

Question 10

Treatment

Answer 10

5-Flurocytosine (Prodrug for 5-FU only activated in fungii)
Polyenes such as Amphotericin B that target ergosterol
Triazole and Echinocandins. Can also apply topical drugs