Bone Infections

Question 1

Causes of Osteomyelitis

Answer 1

Haematogenous and non Haematogenous

Question 2

Pathophysiology of Osteomyelitis

Answer 2

Bactereamia or Septicaemia will allow the bacteria to become stuck in the sinusoids of the bone. Additionally flow is slow in these regions. Lack of immmune survalence will allow growth and abscess formation. Abscess can now expand and grow to move into blood or can invade shaft of bone

Question 3

Bones commonly associated with Osteomyelitis

Answer 3

Femur, Humerous and Tibia. Can also be seen in pelvis and vertebrae

Question 4

Complications of Osteomyelitis in young

Answer 4

The blood vessels from bone penetrate joint and therefore can cause septic arthritis

Question 5

Causes of septic artritis

Answer 5

Haematogenous and non Haematogenous

Question 6

bacterial agents that can cause Osteomyelitis in adults

Answer 6

Staph, group A strep, Kingella kingae and salmonella

Question 7

bacterial agents that can cause Osteomyelitis in neonates

Answer 7

Group B strep, HIB and other gram negative bacteria

Question 8

bacterial agents that can cause Osteomyelitis in trauma

Answer 8

Coaggulase negative staph

Question 9

bacterial agents that can cause Osteomyelitis in Post Chicken Pox

Answer 9

Group A Strep

Question 10

bacterial agents that can cause Osteomyelitis in developing countries?

Answer 10

TB

Question 11

bacterial agents that can cause Osteomyelitis in sneaker penetration

Answer 11

Pseudomonas

Question 12

Best treatment

Answer 12

Without resistance = flucloxacillin and for resistant MRSA vancomycin. with neonates usually throw in a cephlotaxin for gram negative bacteria. For pseudomonas throw in timentin (ticarcillin and cluvanic acid) and gentimicin.

Question 13

Duration of treatment

Answer 13

3-5 days for uncomplicated cases not 4-6 weeks as previously done