Antibiotics

Question 1

MSSA

Answer 1

Flucloxacillin

Question 2

MRSA

Answer 2

Vacomycin

Question 3

Streptococcus (group B)

Answer 3

Benzylpencillin

Question 4

Enterococcus

Answer 4

Amoxycillin

Question 5

MSSA and Strept co infection

Answer 5

Cephlahexin/cephazolin

Question 6

Gram negative

Answer 6

Gentamicin

Question 7

Pseudomonas

Answer 7

Ciprofloxacin/pipercillin/ticocilliin and tazobactam

Question 8

Anaerobes and parasites

Answer 8

Metronidazole

Question 9

GP and GN

Answer 9

Amoxyclav

Question 10

UTI

Answer 10

Trimetoprim

Question 11

Everything

Answer 11

Meropenem

Question 12

TB

Answer 12

• Isoniazid
• Rifamycin
• Pyrazidamine
• Ethambutol

Question 13

Meningitis

Answer 13

3rd generation cephlasporin (ceftriaxone) and penicillin/gentamicin if <3 months (listeria coverage) with vancomycin if Strep is suspected

Question 14

Encephalits + Meningitis

Answer 14

3rd generation cephlasporin + acyclovir

Question 15

Gonorrhoea

Answer 15

Ceftriaxone and Azithromycin

Question 16

Chlamydia

Answer 16

Azithromycin and Doxycycline

Question 17

Trichomonas Vaginalis

Answer 17

Metronidazole or Tinidazole

Question 18

Treponema pallidum

Answer 18

Benzylpenicillin

Question 19

Mycoplasma genitalium

Answer 19

Azithromycin

Question 20

Fungal Infections

Answer 20

5-Flurocytosine (Prodrug for 5-FU only activated in fungii)
Polyenes such as Amphotericin B that target ergosterol
Triazole and Echinocandins. Can also apply topical drugs

Question 21

H. pylori

Answer 21

Amoxycillin, clarithromycin and PPI (omeprazole)

Question 22

Community Acquired Pneumonia (CAP)

Answer 22

Mild
		§ Amoxycillin or Doxycillin
	Moderate
		§ Benzylpenicllin + Doxycycline
	Severe
		§ Ceftriaxone + Azithromycin
Consider Vancomycin/Flucloxacillin if Staph or Oseltamivir if Influenza

Question 23

HAP

Answer 23

Mild - Amoxycillin Clavulanate
Moderate - Ceftriaxone
Severe - Piperacillin /Tazobactum

Question 24

Cystitis

Answer 24

○ Trimethoprim (not pregnant women)
○ Cephalexin
○ Amoxycillin Clav
○ Remove Catheter

Question 25

Pyelonephritis

Answer 25

○ AmoxyClav (Mild)
○ Ceftriaxone (Moderate)
○ Piperacillin/Tazobactum (severe)

Question 26

Intra-Abdominal infections

Answer 26

Ceftriaxone (Gram negatives) + Metrionidazole (Anaerobic) and Ampicillin (enterococcus)

Question 27

Cellulitis

Answer 27

Flucloxacillin, but if allergic cefazolin/cephalexin (mild) or Clindamycin for severe allergies

Question 28

IV related sepsis

Answer 28

Piperacillin/Tazobactum (Psuedomonas) + Vancomycin (MRSA)

Question 29

Infective Endocarditis

Answer 29

Benzylpenicillin, Flucloxacillin and Ceftrixone or if a prosthetic valve is invovled use Vancomycin instead of benzylpenicillin

Question 30

Osteomyelitis

Answer 30

Without resistance = flucloxacillin and for resistant MRSA vancomycin. with neonates usually throw in a cephlotaxin for gram negative bacteria. For pseudomonas throw in timentin (ticarcillin and cluvanic acid) and gentimicin.