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Microbiology > Mycobacterium Tuberculosis > Flashcards

Mycobacterium Tuberculosis Flashcards

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Biology 101 flashcards
0
Q

AFB and gram + bacilli aerobic, NM, NS, NE; requires enriched media and 5-10% of CO2.

A

Mycobacterium tuberculosis

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1
Q

Also known as Koch bacilli, AFB or Tubercle bacilli, Captain of all men of death.

A

Mycobacterium tuberculosis

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2
Q

Slow grower with a generation time of 20 hours; multiply by fermentation; contains much granules; requires whole egg for growth; produces cauliflower like growth on culture medium, luxuriant growth (eugonic); causes tuberculosis in man; long, slender, granular curved or rounded end.

A

Mycobacterium tuberculosis

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3
Q

Medium used in mycobacterium tuberculosis.

A

Lowenstein, petroffs, Dorset’s, corpers

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4
Q

Pathogenecity of mycobacterium tuberculosis

A

No toxins produced

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5
Q

Spinal disease of TB

A

Pott’s disease

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6
Q

Skin disease of TB

A

Lupus Vulgaris

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7
Q

Cervical lymph nodes disease of TB

A

Scrotula

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8
Q

Also know as leprae bacilli, hansens bacilli

A

M.Leprae

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9
Q

exhibits cigar packet arrangement
Non culturable on artificial medium but can be maintained in the footpads of armadillo
Causes leprosy

A

M.leprae

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10
Q

Anesthetic type; non-progressive and benign with few organism on skin lesions; + leprominb test

A

Paucibacillary (Tuberculoid Leprosy)

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11
Q

Nodular type; course is progressive and malign with numerous organisms on skin lesions: - lepromin test

A

Multi bacillary (Lepromatous leprosy)

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12
Q

Differentiating point of M.gordonae from M.scrofulaceum

A

Tween 80
+ M.gordonae
- M.scrofulaceum

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13
Q

Differentiates M.fortuitum-Chelonei + from M.phlei -

A

Arylsulfatase test

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14
Q

M.fortuitum +

A

Iron Uptake test

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15
Q

Differentiates M.flavescens + from M.szulgai -

A

NaCl tolerance test

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16
Q

Causes TB in cows; source of Bacille Calmette Guerin

A

M.bovis

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17
Q

Pigment colonies presence of light

A

Photochromogens

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18
Q

Photochromogens

A

M.szulgai

M.kansasii/M.simiae/M.marinum

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19
Q

Pigments colonies in the presence of darkness/light

A

Scotochromogens

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20
Q

Schotochromogens

A

M.scrofulaceum
M.szulgai
M.gordonae
M.xenopi

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21
Q

Non-Photochromogens and Rapid Growers; - to niacin and nitrate, + tween 80 and heat stable catalase

A

M.malmoense

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22
Q

Non-photochromogens and Rapid Growers; requires Hemin for growth.

A

M.haemophilum

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23
Q

Non-photochromogens and Rapid Growers; battery bacillus; all tests are - except for the heat stable catalase and pyrazinamidase test

A

M.avium-intracellulare

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24
Q

Non-photochromogens and Rapid Growers; may be isolated from gastric lavage

A

M.gastri

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25
Q

The rapid growers;

+ pink to red color

A

Arysulfatease test

26
Q

Strongly + to Arysulfatease test

A

M.fortuitum

27
Q

+ to Arysulfatease test

A

M.chelonei

28
Q

Negative or weakly + Arysulfatease test

A

M.phlei and M.smegmatis

29
Q

The slow growers. Positive

A

Niacin test

30
Q

Gm+ bacilli, NM, NE, alpha hemolytic on BAP. Catalase, INDOLE, oxidase and nitrate negative; ferments glucose and lactose. May cause erysipeloid. H2s positive, produce h2s in the butt of TSI media; is better know as veterinary pathogen than as a human pathogen.

A

Erysipelothrix rhusiopathiae

31
Q

Colonies of Erysipelothrix rhusiopathiae were described as

A

Lampbrush or test tube brush.

32
Q

When cultured on blood agar or some other nutrient medium Erysipelothrix rhusiopathiae forms.

A

Notably large colonies.

33
Q

Treatment of Erysipelothrix rhusiopathiae usually consist of

A

Penicillin G, ampicillin or cephalonthin

34
Q

Most clinical strains of Erysipelothrix rhusiopathiae have been found to be resistant

A

Super-antibiotic vancomycin

35
Q

Small grm + coccobacilli, NAF, shows tumbling motility; Can grow on 25-35,40 and 42C; catalase and vp test +; indole, oxidase and urease test negative; ferments glucose, maltose; bile Esculin hydrolysis +

A

Listeria Monocytogenes

36
Q

Listeria monocytogenes on BAP

A

Produce a narrow band band of beta hemolysis

37
Q

On agar surface the Erysipelothrix rhusiopathiae

A

Produce umbrella like growth “Inverted Chrismtas tree pattern

38
Q

Erysipelothrix rhusiopathiae can cause

A

Listeriosis, Meningitis, Meningoencephalitis and perinatal septicemia.

39
Q

Two species of human pathogenic significance in listeria monocytogenes

A

Listeria monocytogenes and listeria Ivanovo

40
Q

Susceptibility test for Listeria Monocytogenes. Suspension into rabbit eye or guinea pig. + result purulent conjunctivitis develops after 24 hours.

A

Anton’s test

41
Q

Commonly known as probiotic or good bacteria. Normal flora of the mouth, GIT and vaginal canal. Rare cause of bacteremia and pneumonia; produce large qnty of lactic acid. Gm+, catalase -, pleomorphic, NM, H2S -, does not hydrolyze Esculin

A

Lactobacillus acidophilus

42
Q

If one fermenter is produced

A

Homofermenter

43
Q

Numerous fermentation and there are products other than lactic acid

A

Heterofermenter

44
Q

Common name of Lactobacillus acidophilus

A

Doderlein bacillus

45
Q

Products like yoghurt

A

L.bulgaricus

46
Q

For yakult milk

A

Lactobacillus-shirota strain

47
Q

Swiss cheese

A

L.delbruecki subsp. bulgaricus

48
Q

Can also be found in the intestine

A

L.cassei

49
Q

Facultative anaerobe and multiplied by transverse fission; all are M producing axial fibrils, a long flagellum like intracellular organelle that are responsible for its motility. Unicellular organisms with flexus structure. Dark field microscopy

A

Spirochetes

50
Q

Causative agent of syphillis

A

T.pallidum

51
Q

Disease of blood vessel and peri vascular areas

A

Syphillis

52
Q

Commonly observed during the early stages when treated with penicillin

A

Jarisch-Herxheimer Reaction

53
Q

Closely resembles tawa

A

Bejel

54
Q

Disease of bones and skin, non verenal, transmitted thru aids of of flies; causative agent of yaws

A

T.pertenue

55
Q

Infection if the feet which cause a crippling form of disease

A

Crab yaws

56
Q

Affects only the skin and becomes de pigmented; causative agent of carate or punta which is characterized by hyperpigmented lesion.

A

T.carateum

57
Q

Thin, flexible organisms with tightly coiled spirals and one or both ends mag be bent to form a hook. Strict aerobic, oxidase and catalase +, peroxidase +; causative agent of Weil’s disease

A

Leptospira

58
Q

Other names of leptosira

A

Swineherd’s disease, Fort Bragg Fever, Pretibial Fever, canicola fever and autumnal fever

59
Q

2 recognized fever of leptosira

A

Leptosira interrogans and leptosira biflexa

60
Q

Disease produced is relapsing fever, tick fever, borreliosis or famine fever. Loosely coiled, irregular in shape, highly flexible spiral organisms, motile, microaerophilic. Can be visualized by staining with aniline dyes.

A

Borria

61
Q

Louseborbe or epidemic relapsing fever which is transmitted to man by the human body louse.

A

Borrelia recurrentis

62
Q

Tick borne or endemic relapsing fever which is transmitted to man by ticks:Ornithodoros species.

A

Borrelia turicatae and Borrelia parkeri

63
Q

Causative agent of avian spircohetosis

A

Borrelia anserina

Microbiology (7 decks)

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