Mutliple Sclerosis Flashcards

1
Q

What is multiple sclerosis?

A

A chronic autoimmune inflammatory condition that results in the demyelination of the central nervous system

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2
Q

What type of hypersensitivity reaction is MS?

A

Type IV

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3
Q

What are the types of MS?

A
  1. Primary Progressive
  2. Relapsing-remitting
  3. Progressive-relapsing
  4. Secondary progressive
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4
Q

What is Primary Progressive MS?

A

Steady accumulation of disability

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5
Q

What is Relapsing-remitting MS?

A

Unpredictable attacks with COMPLETE recovery between

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6
Q

What is Progressive-relapsing MS?

A

Steady decline with attacks

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7
Q

What is Secondary progressive MS?

A

Initially had COMPLETE recovery but suddenly becomes steady decline

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8
Q

What are the signs for MS?

A
  1. Lhermitte’s
  2. Uthoff’s
  3. Internuclear ophthalmoplegia
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9
Q

What is Lhermitte’s sign?

A

Flexion of the neck causes a shooting electrical pain down the spine

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10
Q

What is Uthoff’s sign?

A

Neuro signs are worsened after an increase in temperature (showers/baths etc)

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11
Q

What is Internuclear ophthalmoplegia?

A

A lesion in the medial longitudinal fasciculus so the medial rectus of the ipsilateral eye does not function to adduct and you get nystagmus of the contralateral eye

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