Mutation Flashcards

1
Q

Structural mutations

A

Deletion, insertion, duplication, inversion, reciprocal translocation, fusion, fission, chromosomal duplication, whole genome duplication

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2
Q

Linkage disequilibrium

A

When an allele at one locus is found together in a population more often than expected by chance with an allele at a second locus
Can be produced by natural selection (epistasis)

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3
Q

Mutation rate

A

Probability that offspring carries a mutation

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4
Q

Epistasis

A

A situation in which the effect of an allele at one locus depends on the allele at a second locus
Combination leads to higher fitness

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5
Q

Pleiotropy

A

A single mutation affects multiple traits

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6
Q

Two effects of mutation

A

Pleiotropy

Effects on fitness

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7
Q

High mutation rates

A

In populations with low genetic variation

Asexual species

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8
Q

Selection coefficient

A

Effect mutation has on survival
-most mutations
Eg: SC= -0.1 —> decreases survival by 10%

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9
Q

Are mutations random

A

Transition mutations are more likely than transversions
-not all mutations equally likely
Mutations are random with respect to what will increase fitness

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10
Q

Maternal effect

A

When the genotype or phenotype of the mother directly influences the phenotype of her offspring

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