Prokaryotic Genome Evoluton Flashcards
Prokaryote
Unicellular Lacks nucleus Lacks mitochondria Lacks membrane bound organelles Have ribosomes
Pangenome
All genes that are present in all individuals/populations of a species
-core + accessory genome
Core genome
All genes that are common between individuals/populations of a species
Accessory genome
All genes that are present in only a subset of individuals/populations of a species
Genes moved nuclear genome can be recognized by
Homology to bacterial genes
Different GC content
Lack of introns
Nonorthologous gene displacement
Genes that are dissimilar in sequence perform the same function
Selectionist view on changes in GC content
Regards GC content as a trait that is determined by selective forces
- adaption to intrinsic/extrinsic conditions
Changes in codon usage to explain changes in GC content
Due to gene dosage of tRNAs
Strand dependent mutation patters explaining GC content
Certain types of point mutations occur at different frequencies in leading and lagging strands
Leads to strand dependent substitution patterns