Mutagens

Question 1

Alkylating Agents

Answer 1

Alkylation of G causes basepair w/ T instead of C –> incorrect base pairing during replication if not fixed by BER.

Question 2

Benzo[a]pyrine

Answer 2

Mutagen found in cigarette smoke + red meats. When added to G in template for DNA replications it can cause G –> T mutations.

Question 3

Intercalating Compounds

Answer 3

Exogenous mutagens that can be inserted into DNA or cause deletion mutations.