Muskelrelaxantien Flashcards

1
Q

Atracurium Dosierung

  • Intubation
  • Wiederholungsdosis
  • Infusion
A
  • 0,3 - 0,6mg/kg
  • 0.1-0.2mg/kg
  • 0,3 - 0,6mg/kg/h

Ideal body weight

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2
Q

Eliminierung Atracurium

A
  • Hofmann Elimination, pH und temperaturabhängig, wird zu laudanosine
  • unspezifische Esterhydrolise
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3
Q

Wirkdauer Atracurium

A

20 - 30 Minuten

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4
Q

Dosierung Cisatracurium

  • Intubation
  • Wiederholungsdosis
  • Infusion
A
  • 150 micrograms/kg
  • 30 micrograms/kg alle 20 Minuten
  • 0,06 - 0,18mg/kg/hr
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5
Q

Wirkdauer Cisatracurium

A

55 Minuten

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6
Q

Dosierung Dantrolene

A

1mg/kg alle 5 Minuten bis maximal 10mg/kg

Hyperkaliämie in Kombination mit Calcium - Kanalblockern
Plazentagängig

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7
Q

Dosierung Mivacurium

  • Intubation
  • Wiederholungsdosis
  • Infusion
A
  • 0,07 - 0,25mg/kg
  • 0,1mg/kg
  • 0,4 - 0,6mg/kg/hr
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8
Q

Wirkdauer Mivacurium

A
- je nach Dosierung:
0,07 -> 13min
0,15 - > 16min
0,2 -> 20min
0,25 -> 23min

Jeweils /kgKG; insgesamt stark variabel

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9
Q

Dosierung Pancuronium

  • Intubation
  • Wiederholungsdosis
A
  • 0,1mg/kg

- 0,02mg/kg

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10
Q

Dosierung und Wirkdauer Pipecuronium

A
  • Intubation 0,08mg/kg
  • Wiederholung 0,01 - 0,04mg/kg

Wirkt 45 - 120 min

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11
Q

Dosierung Rocuronium

  • Intubation
  • Wiederholungsdosis
  • Infusion
A
  • 0,6 - 1mg/kg
  • 0,1 - 0,15mg/kg
  • 0,3 - 0,6mg/kg/h
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12
Q

Dosierung Succinylcholin

A

1-1,5mg/kg (Infusion 0,5-10mg/min)

Kinder: 3-4mg/kg i.m.

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13
Q

Besonderheiten Succinylcholin

A
  • Depolarisierend
  • Phase II Block mit Wiederholungsdosen (>8mg/kg)
  • Bradykardie bei der Zweitdosis - muskarinerge Rezeptoren im Sinusknoten
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14
Q

Dosierung Vecuronium

A
  • 80 - 100µg/kg
  • 20 - 30 µg/kg
  • 0,8 - 1,4µg/kg/min
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15
Q

Wirkdauer Vecuronium

A

45 Minuten

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16
Q

Dosierung Sugammadex

A

2-4mg/kg

16mg/kg im Notfall zur sofortigen Aufhebung der Muskelrelaxation