Musculoskeletal System: The Skeleton Flashcards
(127 cards)
How many bones does a newborn have?
350
How many bones does an adult human have?
206
What are the functions of the skeleton?
Support, movemement, protection, storage of minerals and blood cell production
What is the support purpose of the skeleton?
Structural and as a framework for the attachment of soft tissues and organs
What is the movement functions of the skeleton?
Attachment of skeletal muscle to bones either side of joints enables movement
What are the protective functions of the skeleton?
Many soft tissues and organs are surrounded by bone for protection
What is the mineral storage function of the skeleton?
Lipids are important for energy reserves and calcium salts are important for maintaining normal concentrations of calcium and phosphate ions in body fluids
What is an epiphysis?
Rounded bit at the end of the bone that contributes to a joint
What is a metaphysis?
Long bones containing the growth plate
What is the medullary cavity?
Hollow part of bone containing bone marrow
What is a synonym for the Epiphysial line?
Cartilage plate
What are the only cell types that are found in healthy cartilage?
Chondrocytes
What do chondrocytes mainly produce?
The cartilaginous matrix (made of collagen)
Does cartilage have a vascular supply?
No
How does cartilage get its blood supply?
From the vasculated tissue around it
What happens in the first stage of endochondral ossification?
Chondrocytes increase in size while the matrix calcifies around them, so they apoptose
What happens in the third stage of endochondral ossification?
Cartilage becomes vasculated and is replaced by trabecular bone.
Fibroblasts differentiate into osteoblasts
What happens in the second stage of endochondral ossification?
Blood vessels grow into the perichondrium and cells differentiate into osteoblasts
What is the periosteum?
The bit around the edge of the cartilage shaft
What is a primary ossification centre?
Where the cartilage matrix is replaced by trabecular bone first
What happens in the fourth stage of endochondral ossification?
Wave of ossification spreads towards the end of long bone
Osteoclasts adsorb bone, leaving a marrow cavity
Bone grows inwards forming the compact bone
What happens in the fifth stage of endochondral ossification?
Capillaries and osteoblasts migrate into the epiphyses and ossification begins
What is the purpose of the epiphyseal growth plate?
Allows interstitial growth in bone
What is an articular centre?
Articulates with cartilage from another bone and prevents bone on bone articulations