Musculoskeletal System: The Skeleton Flashcards
How many bones does a newborn have?
350
How many bones does an adult human have?
206
What are the functions of the skeleton?
Support, movemement, protection, storage of minerals and blood cell production
What is the support purpose of the skeleton?
Structural and as a framework for the attachment of soft tissues and organs
What is the movement functions of the skeleton?
Attachment of skeletal muscle to bones either side of joints enables movement
What are the protective functions of the skeleton?
Many soft tissues and organs are surrounded by bone for protection
What is the mineral storage function of the skeleton?
Lipids are important for energy reserves and calcium salts are important for maintaining normal concentrations of calcium and phosphate ions in body fluids
What is an epiphysis?
Rounded bit at the end of the bone that contributes to a joint
What is a metaphysis?
Long bones containing the growth plate
What is the medullary cavity?
Hollow part of bone containing bone marrow
What is a synonym for the Epiphysial line?
Cartilage plate
What are the only cell types that are found in healthy cartilage?
Chondrocytes
What do chondrocytes mainly produce?
The cartilaginous matrix (made of collagen)
Does cartilage have a vascular supply?
No
How does cartilage get its blood supply?
From the vasculated tissue around it
What happens in the first stage of endochondral ossification?
Chondrocytes increase in size while the matrix calcifies around them, so they apoptose
What happens in the third stage of endochondral ossification?
Cartilage becomes vasculated and is replaced by trabecular bone.
Fibroblasts differentiate into osteoblasts
What happens in the second stage of endochondral ossification?
Blood vessels grow into the perichondrium and cells differentiate into osteoblasts
What is the periosteum?
The bit around the edge of the cartilage shaft
What is a primary ossification centre?
Where the cartilage matrix is replaced by trabecular bone first
What happens in the fourth stage of endochondral ossification?
Wave of ossification spreads towards the end of long bone
Osteoclasts adsorb bone, leaving a marrow cavity
Bone grows inwards forming the compact bone
What happens in the fifth stage of endochondral ossification?
Capillaries and osteoblasts migrate into the epiphyses and ossification begins
What is the purpose of the epiphyseal growth plate?
Allows interstitial growth in bone
What is an articular centre?
Articulates with cartilage from another bone and prevents bone on bone articulations
How do genetic factors affect bone development?
The overall shape and dimensions of a bone are shaped genetically
How does activity affect bone development?
Bone adapts to meet functional demands
How do nutritional factors affect bone development?
Availability of calcium, phosphate salts, vitamin A, C, D, K and B12
How do hormonal factors affect bone development?
Calcitonin, parathyroid hormone, growth hormone and Estrogen affect calcium levels and bone growth
How do pathological factors affect bone development?
Disease processes like infection, bone tumours and TB
How does age affect bone development?
Loss of calcium and the ability to use it can cause brittle bones which easily fracture
What are the two divisions of the skeleton?
Axial and appendicular
What is the axial skeleton?
Forms central supporting axis of the body
What is the appendicular skeleton?
Bones of the upper and lower limbs, pelvic and pubic girdle
What are the 5 classifications of bone by shape?
long, short, flat, irregular, sesamoid
What are the features of long bones?
Elongated tubular shafts, a central medullary cavity and expanded ends for articulation
What are some examples of long bone?
Femur, humerus and tibia
What are the features of short bones?
Thin outer shell of compact bone with a completely trabecular interior
What are the features of flat bones?
Two shells of compact bone separated by a layer of cancellous bone
What are the features of irregular bones?
Anything that doesn’t fit into any other category
What are the features of sesamoid bones?
Found in tendons
Give some examples of short bones
Carpal bones of the hand and tarsus bones in the foot
Give some examples of flat bones
Frontal and parietal bone, sternum and ribs
Give some examples of irregular bones
Sphenoid bone of the skull
Give some examples of sesamoid bones
Patella
Where is the proximal end of the bone?
Closest to trunk
Where is the neck of a bone?
Narrowing where the shaft meets the epiphysis
Where is the distal end of the bone?
Furthest from the trunk
What is an articular surface of a bone?
Hyaline cartilage that provides wear-resistant lubricated surface to allow two bones to come together
What is a condyle?
Curved articular surface
What is an epicondyle?
Jutting out from the side of an articular condyle