Musculo syst Flashcards

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1
Q

What are the three types of muscles?

A

Skeletal muscle, Smooth muscle, Cardiac muscle

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2
Q

What nervous system innervates skeletal muscle?

A

Somatic nervous system

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3
Q

What gives skeletal muscle its striated appearance?

A

Sacromeres (arrangement of actin and myosin into repeating units)

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4
Q

Why is skeletal muscle multinucleated?

A

It is formed as individual muscles fuse into long rods during development

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5
Q

What characterizes red-fibers/slow-twitch fibers?

A

High myoglobin content, derive energy aerobically, contain many mitochondria, carry out oxidative phosphorylation

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6
Q

What characterizes white fibers/fast-twitch fibers?

A

Less myoglobin, less iron, lighter color, can contract rapidly but fatigue quickly

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7
Q

What is the function of tendons?

A

Anchor muscle to bones

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8
Q

What is a sacromere?

A

Basic contractile unit of skeletal muscle

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9
Q

What are the thick filaments in a sacromere made of?

A

Bundles of myosin

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10
Q

What are the thin filaments in a sacromere made of?

A

Actin, troponin, tropomyosin

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11
Q

What role does titin play in muscle structure?

A

Acts as a spring, anchors actin & myosin filaments together

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12
Q

What is the Z-line in a sacromere?

A

Boundary of each sacromere

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13
Q

What is the A-band in a sacromere?

A

Full thick filaments with any overlap with thin filaments

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14
Q

What happens to the A-band during muscle contraction?

A

It remains constant in size

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15
Q

What is myogenic activity?

A

Contracting of smooth muscles without nervous system input

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16
Q

Where is smooth muscle found?

A

Respiratory tree, Digestive tract, Bladder, Uterus, Blood vessel walls

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17
Q

What is the role of intercalated discs in cardiac muscle?

A

Contain gap junctions allowing rapid & coordinated depolarization

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18
Q

What is the primary function of cardiac muscle?

A

Involuntary contraction

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19
Q

What initiates the depolarization in cardiac muscle?

A

SA node

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20
Q

What neurotransmitter slows the heart rate?

A

Acetylcholine from the vagus nerve

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21
Q

What effect does norepinephrine have on the heart?

A

Increases heart rate and greater contractility

22
Q

Fill in the blank: Calcium release from the _______ triggers muscle contraction.

A

Sarcoplasmic reticulum

23
Q

What happens when acetylcholine binds to the sarcolemma?

A

Opens Na channels, starting an action potential

24
Q

What is the sarcoplasmic reticulum?

A

Modified ER covering that surrounds the myofibrils

25
What is the role of T-tubules?
Propagate action potentials and distribute them to all sacromeres
26
What occurs after calcium ions bind to troponin?
Tropomyosin is moved out of the way, allowing myosin to bind to actin
27
What is tonus in smooth muscle?
A constant state of low level contractions
28
tetanus
muscle is unable to relax due to too frequent contractions
29
Latent period
The time between reaching the threshold and the onset of contraction
30
Simple twitch
Response of single muscule fiber to abbreviate stimulus at the threshold or above it
31
Frequency summation
Frequent and prolonged contractions combined and become stronger and more prolonged
32
What happens to the sarcolemma during relaxation?
It repolarizes
33
What happens to the acetylcholine during relaxation?
It gets degraded by acetylcholinestrase
34
what happens on the sarcolemma when acetylcholine is released?
Na channels open and Na enters the muscle cell
35
Till where do these Na channels open?
till the T-tubule
36
what happens when calcium is released from these sarcoplasmic reticulum?
It attaches to the troponin, which loses the tropomyosin & opens the actin for myosin to bind
37
What happens when ATP attaches to myosin?
Myosin of detaches from the actin
38
What happens to myosin when it hydrolyzes ATP?
It enters high energy state
39
How does myosin bring back and pushes on actin?
it does this when P group is released
40
What happens to the actin when calcium is there?
Calcium binds to troponin which loosens tropomyosin and opens actin for myosin to bind
41
Oxygen debt
the difference between the amount of oxygen needed by the muscles - the actual amount present
42
What are the two reserves muscles have for energy?
creatine phosphate and myoglobin
43
When does muscle become fatigue?
When it starts to produce lactic acid
44
what are the reserves of slow Twitch red muscles?
They use oxidative phosphorylation to make ATP because they have high levels of mitochondria
45
what are the reserves of fast twitch red muscles?
they rely on glycolysis and fermentation to make ATP because they have less mitochondria
46
What happens to oxyhemoglobin curve during exercise?
It shifts to the right Increase concentration of carbon dioxide, hydrogen ions, body temperature
47
How is lactic acid metabolized?
It is converted to pyruvate It needs more oxygen for this
48
muscle spasticity
a condition where muscles become stiff, tight, and resistant to movement
49
Influx
entry of large number of molecules
50
invasive
tending to spread in a quick and aggressive manner