Muscular System Flashcards
What is the area of the sarcomere where only actin is present?
I band
What part of the sarcomere shortens during muscle contraction?
The H-zone (which contains only thick filaments) and the I-band (which contains only thin filaments
What causes different types of muscle fibers to vary in speed of contraction?
Due to the type of ATPase on their myosin heads, this allows for the hydrolysis of ATP into ADP + Pi and ultimate cross-bridge cycling
Hypotonicity
Occurs as a result of damage to the peripheral nervous system and reduced electrolytes which causes muscles to lose tone and thus feel flaccid
Ex: carpal tunnel syndrome - compression of the peripheral never leaves hands feeling weak
Hypertonicity
Occurs as a result of damage to the central nervous system and causes muscles to gain tone and thus feel spastic and rigid
Ex: stroke- causes damage to the CNS, causing muscles to feel stiff
Contraction phase
Calcium binds to troponin-C, triggering a shape change in troponin that causes it to pull tropomyosin away from actin’s myosin binding site
Cross-bridges are established and the H zone begins to shrink