Muscular Flashcards
What are the three muscle types?
Cardiac
Smooth
Skeletal
Plasma Membrane of the muscle cell
Sarcolemma
Cytoplasm of the muscle cell
Sarcoplasm
Smooth ER o muscle cell
Sarcoplasmic Reticulum
Which muscle type contains intercalated discs?
Cardiac Muscle
Skeletal Muscle
- Voluntary?
- Striated?
- Mono- Nucleated or Multi-Nucleated?
Voluntary
Striated
Multi-Nucleated
Cardiac Muscle
- Voluntary?
- Striated?
- Mono- Nucleated or Multi-Nucleated?
Involuntary
Striated
Mono-nucleated
Smooth Muscle
- Voluntary?
- Striated?
- Mono- Nucleated or Multi-Nucleated?
Involuntary
Non-Striated
Mono-Nucleated
Which week of development do skeletal muscles contract by?
7th week
Which cell reserve myoblasts that can form new skeletal muscle?
Satellite Cells
Compare Atrophy vs. Dystrophy
Atrophy -> decrease in muscle diameter when not used
Dystrophy -> increase in muscle diameter during continuous use
What are the connective coverings of Skeletal Muscle and what do they cover?
Epineurium- Covers muscle
Perineurium - Covers muscle fascicle (bundle of fibers)
Endoneurium- Covers muscle fiber
What is a sarcomere?
Arrangement of myofibrils
Which staining is used in Skeletal Muscle?
H&E STAINING
What structure covers the Myofibril?
Sarcoplasmic Reticulum
Fx. of actin & myosin
Contraction
Z-Line
between adjacent sarcomeres
M-Line
connects thick filament lines
H-Zone
Contains thick filaments
Zone of Overlap
Overlap of thick & thin filaments
A-Band
Dark Band
Thick/Thin Filaments
I-Band
Light Band
Thin Filaments
What are thin filaments composed of?
Actin, Nebulin, Troponin, Tropomyosin
What are thick filaments composed of?
Myosin
Fx. of Tropomyosin
Black active site on Actin
What are the fx. of the 3 subunits of Troponin
TnT -> binds to tropomyosin
TnI -> Inhibits interaction
TnC -> Capacity to bind to Ca2+; conformationally change the shape of complex
