Muscle Structure & Function Flashcards
Muscular Connective Tissue @ Macrostructure Level Sarcolema
thin, transparent membrane covering muscle fibers
Muscular Connective Tissue @ Macrostructure Level Endomysium
connective tissue covering sarcolemma/muscle fibers *inner most
Muscular Connective Tissue @ Macrostructure Level Perimysium
connective tissue covering groups of muscle fibers *middle
Muscular Connective Tissue @ Macrostructure Level epimysium
endomysium and perimysium are continues with epimysium *outermost
Muscular Connective Tissue @ Macrostructure Level myofilaments
actin and myosin
Muscle>muscle fascicles>muscle fiber> myofibril>myofilaments
all of these blend to form connective tendon sheath at myotendinous junction
SR (Sarcoplasmic reticulum) T-Tubule (transverse tubules)
storage site for calcium T-tubule: connectors of all fibers
Sarcomere
thick and thin alternations form distinctive striped pattern Z to Z

myosin
Thick filaments

actin
thin filaments

titin
links myosin to Z line

A Band portion
I-Band
portion that extends over both lenght of thick and small portion of thin filament
(myosin & actin)
Iband ( only thin)
hzone- no overlapping
What is attached to actin
Myosin
Globular enlargments call head groups for binding sites for acti that swivel, responsible for power stroke of head, splits ATP
Sliding filament Theory
myosin turns ATP to ADP and Pi, this energizes head
to be continued
Tropomysosin
Troponin
regulatory protein that blocks myosin binding site on actin
Troponin- represents switch that binds calcium and blocks neutralizes tropomyosin
Motor Unit Structure
Efferent
A in
E Out
Starts at anterior horn, goes through axon to motor endplats at each muscle fiber
Type I Oxidative Efferent
Type IIB glycolytic of efferent neuron
large diameter, white, sparse capillary supply, fast contraction speed, fast fatigue rate,
So generate greater force but fatigue quickly
AP (action potential) causes release of what in NMJ
acetylcholine
Agonist (prime mover
Antagonist Muscles
opposite effect of agonist
permits joint action by shortening or passively elongating
Fixers/ Stabilizers are supporters
