Muscle physiology Flashcards

1
Q

two main types of muscle

A

striated muscle

smooth muscle

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2
Q

what type of muscle do skeletal and cardiac muscle belong to?

A

striated

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3
Q

what is an example of smooth muscle?

A

line circulatory vessels

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4
Q

what is skeletal muscle?

A

a type of striated muscle, controlled by the voluntary (somatic) nervous system
aids locomotion

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5
Q

what is cardiac muscle?

A

a type of striated, myogenic muscle, controlled by the autonomic nervous system (involuntary)

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6
Q

tendon

A

a large piece of connective tissue

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7
Q

myomere

A

blocks of muscle along side of body

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8
Q

role on titin

A

anchors myosin to the z line

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9
Q

how can muscle tension be increased?

A

muscle fibre stimulated again, before it completely relaxed = tetanus

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10
Q

motor unit

A

a group of muscle fibres that get all their signals from same single motor neuron

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11
Q

asynchronous recruitment

A

not all muscle fibres recruited at once, but AT RANDOM - can delay fatigue

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12
Q

how can muscle fatigue be delayed?

A

asynchronous recruitment

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13
Q

what is the ‘endurance’ muscle fibre?

A

type 1, dark fibre (=lots of myoglobin) - marathon runner dominant, slow oxidative

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14
Q

what is the ‘sprinter’ muscle fibre?

A

type 2b/2a, light fibre, fast glycolytic/fast oxidative

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15
Q

how is muscle force regulated?

A

electricl signals dictate muscle force

contractile response lags behind action potential

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16
Q

structural & biochemical features of skeletal muscle which aids O2 delivery

A

weaving muscle capillaries

increased pH because of CO2 released leads to offload of O2 as lower affinity of haemoglobin to O2

17
Q

neurogenic contraction

A

signal comes from outside of muscle

18
Q

smooth muscle contraction

A

made up of alpha actin
no overlap of thick or thin filaments
availability of myosin to actin is regulated by myosin light chain
upon excitation…
Ca2+ binds to calmodulin
Ca2+ and calmodulin complex activates myosin light chain kinase
myosin light chain kinase phosphorylates myosin light chain
NOW myosin head is free to bind to alpha actin