Muscle Flashcards
What are the two major gross changes with muscle pathology?
size
color
What are possible causes for pale muscle?
Inflammation
Mineralization
Fat infiltration
What are possible causes for nodules in muscle?
Parasites
Abscess
What are possible causes for dark red mottling muscle?
vascular change
What are possible causes for green muscle?
eosinophilic inflammation
putrefaction
What is the possible cause for black muscle?
melanosis
What will soft muscle be telling us?
fatty infiltration
What will hard muscle indicate?
calcification
fibrosis
What stain is used to differentiate collagen from other tissues? What is it useful for identifying?
Trichrome (Masson’s)
identifies fibrosis, chronic myopathy
What stain enhances the view of cross striations?
PTAH
What stain detects glycogen and proteoglycans?
PAS
What stain differentiates myofiber types? What condition is the sample in for use of this test?
ATPase
only performed on frozen (unfixed) sections!
