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39 Inhibitors Of Bacterial Protein Synthesis > Mupirocin, Linezolid > Flashcards

Mupirocin, Linezolid Flashcards

1
Q

Protein synthesis inhibitors that are not 30S or 50S inhibitors. (2 drugs)

A

Mupirocin

Linezolid

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2
Q

Linezolid - MOA

A

Prevents formation of the 70S initiation complex

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3
Q

Linezolid - indications

A

Vancomycin-res E. faecicum, MRSA pneumonia, skin & soft tissue inf
Necrotizing fasciitis

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4
Q

Linezolid - adverse effects

A 
Thrombocytopenia (renal insuff or prolonged therapy)
Serotonin toxicity (with selective serotonin reuptake inhibitors)
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5
Q

Mupirocin - MOA

A

Prevents formation of isoleucyl tRNA

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6
Q

Mupirocin - indications

A

Impetigo (topical)

Eradicate nasal colonization of MRSA

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39 Inhibitors Of Bacterial Protein Synthesis (6 decks)

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